Children's Hospital of Pittsburgh of UPMC, PA, USA.
Neurosurg Focus. 2011 Aug;31(2):E3. doi: 10.3171/2011.5.FOCUS1196.
OBJECT Sagittal craniosynostosis is the most common form of craniosynostosis and is commonly treated within the first year of life. Optimal treatment of patients older than 1 year of age is not well characterized. The authors reviewed cases of sagittal craniosynostosis involving patients who were treated surgically at their institution when they were older than 1 year in order to determine the rate of intracranial hypertension (ICH), potential to develop nonhealing cranial defects, and the need for various surgical procedures to treat the more mature phenotype. METHODS A retrospective chart review was conducted of all cases in the Children's Hospital of Pittsburgh Neurosurgery Database involving patients who underwent cranial vault remodeling for scaphocephaly after 1 year of age between October 2000 and December 2010. RESULTS Ten patients were identified who met the inclusion criteria. Five patients underwent anterior two-thirds cranial vault remodeling procedures, 3 patients underwent posterior vault remodeling, and 2 patients underwent 2-staged total vault remodeling. All patients had improved head shapes, and mean cephalic indices improved from 65.4 to 69.1 (p = 0.05). Six patients exhibited signs of ICH. No patients with more than 3 months of follow-up exhibited palpable calvarial defects. CONCLUSIONS Patients with sagittal synostosis treated after 1 year of age demonstrate increased rates of ICH, warranting diligent evaluations and surveillance to detect it; rarely develop clinically significant cranial defects if appropriate bone grafting is performed at the time of surgery; and achieve acceptable improvements in head shape.
矢状缝颅缝早闭是最常见的颅缝早闭类型,通常在生命的第一年进行治疗。1 岁以上患者的最佳治疗方法尚未得到很好的描述。作者回顾了在他们的机构接受手术治疗的矢状缝颅缝早闭患者的病例,这些患者在 1 岁以上时接受治疗,目的是确定颅内高压(ICH)的发生率、潜在的无法愈合的颅骨缺陷以及需要各种手术来治疗更为成熟的表型。
对 2000 年 10 月至 2010 年 12 月期间在匹兹堡儿童医院神经外科数据库中接受颅骨穹窿成形术治疗斜头畸形的所有病例进行回顾性图表审查,这些患者的年龄均在 1 岁以上。
确定了符合纳入标准的 10 名患者。5 名患者接受了前 2/3 颅骨穹窿成形术,3 名患者接受了后颅穹窿成形术,2 名患者接受了 2 期全颅穹窿成形术。所有患者的头型均得到改善,头围指数平均值从 65.4 增加到 69.1(p=0.05)。6 名患者出现 ICH 迹象。在超过 3 个月的随访中,没有患者出现可触及的颅骨缺陷。
1 岁以上接受治疗的矢状缝颅缝早闭患者 ICH 发生率增加,需要进行仔细的评估和监测以发现 ICH;如果在手术时进行适当的骨移植,很少会出现临床上显著的颅骨缺陷;并且可以获得可接受的头型改善。