Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
Med J Aust. 2011 Aug 1;195(3):S31-7. doi: 10.5694/j.1326-5377.2011.tb03263.x.
To determine whether the addition of cognitive behaviour therapy and motivational interviewing (CBT/MI) to standard alcohol and other drug (AOD) care improves outcomes for young people with comorbid depression and substance misuse.
Participants were young people with comorbid depression (Kessler Psychological Distress Scale score ≥ 17) and substance misuse (mainly alcohol and/or cannabis) seeking treatment at two youth AOD services in Melbourne, Australia. The study was conducted between September 2006 and September 2008. Sixty young people received CBT/MI in addition to standard care (SC) (the SC+CBT/MI group) and 28 received SC only (the SC group).
Depressive symptoms and AOD use in the previous 30 days, measured at baseline and at 3-month and 6-month follow-up.
Compared with participants in the SC group, those in the SC+CBT/MI group showed significant reductions in depression and cannabis use and increased social contact and motivation to change substance use at 3-month follow-up. However, at 6-month follow-up, the SC group had achieved similar improvements to the CBT/MI group on these variables. All young people achieved significant improvements in functioning and quality of life variables over time, regardless of treatment group. No changes in AOD use were found in either group at 6-month follow-up.
The delivery of CBT/MI in addition to SC may achieve accelerated treatment gains in the short term.
确定在标准的酒精和其他药物（AOD）治疗基础上增加认知行为疗法和动机访谈（CBT/MI）是否能改善共病抑郁和物质使用障碍的年轻人的预后。
参与者为在澳大利亚墨尔本的两家青年 AOD 服务机构寻求治疗的共病抑郁（Kessler 心理困扰量表评分≥17）和物质使用障碍（主要为酒精和/或大麻）的年轻人。该研究于 2006 年 9 月至 2008 年 9 月进行。60 名年轻人在接受标准治疗（SC）的基础上接受 CBT/MI（SC+CBT/MI 组），28 名年轻人仅接受 SC（SC 组）。
在基线以及 3 个月和 6 个月随访时测量的过去 30 天的抑郁症状和 AOD 使用情况。
与 SC 组的参与者相比，SC+CBT/MI 组在 3 个月随访时显示出抑郁和大麻使用减少，社交接触增加，改变物质使用的动机增强。然而，在 6 个月随访时，SC 组在这些变量上取得了与 CBT/MI 组相似的改善。所有年轻人无论治疗组如何，随着时间的推移，在功能和生活质量变量上都取得了显著的改善。在 6 个月随访时，两组的 AOD 使用均无变化。
在 SC 基础上提供 CBT/MI 可能会在短期内实现加速治疗效果。
