睾丸/睾丸旁纤维性假瘤冰冻切片分析的作用：五例经验
Role of frozen section analysis of testicular/paratesticular fibrous pseudotumours: a five-case experience.
作者信息
Gordetsky Jennifer, Findeis-Hosey Jennifer, Erturk Erdal, Messing Edward M, Yao Jorge L, Miyamoto Hiroshi
机构信息
Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY; Department of Urology, University of Rochester Medical Center, Rochester, New York, USA.
出版信息
Can Urol Assoc J. 2011 Aug;5(4):E47-51. doi: 10.5489/cuaj.10144.
BACKGROUND
Fibrous pseudotumours of the testicular and paratesticular tissues are fibroinflammatory reactive lesions that can clinically mimic neoplasms. Very little is known about the role of frozen section analysis (FSA) for these lesions in terms of intraoperative surgical management.
METHODS
We recently experienced 5 patients with testicular/paratesticular fibrous pseudotumours in whom frozen sections were used to demonstrate its non-neoplastic nature prior to the decision for radical surgery.
RESULTS
In 2 cases, FSA resulted in testicular-sparing surgery. In contrast, the remaining 3 cases ultimately underwent radical orchiectomy, due to questionable viability of the testicle involved by inflammatory/infiltrative lesions and in 1 case a slight possibility of lymphoproliferative malignancy.
CONCLUSION
Urologists should be aware of this entity and its gross features, such as firm masses and diffuse fibrous proliferation encasing the testicle to help determine intraoperative management. In select cases, intraoperative FSA is helpful in obviating radical orchiectomy.
背景
睾丸及睾丸旁组织的纤维性假瘤是纤维炎性反应性病变，临床上可酷似肿瘤。关于冰冻切片分析（FSA）在这些病变的术中手术管理方面的作用，所知甚少。
方法
我们最近遇到5例睾丸/睾丸旁纤维性假瘤患者，在决定行根治性手术前，通过冰冻切片证实其非肿瘤性质。
结果
2例患者经FSA后行保留睾丸手术。相比之下，其余3例最终接受了根治性睾丸切除术，原因是受累睾丸因炎性/浸润性病变而存活可疑，以及1例存在淋巴增殖性恶性肿瘤的微小可能性。
结论
泌尿外科医生应了解这一实体及其大体特征，如质地坚硬的肿块和包绕睾丸的弥漫性纤维增生，以帮助确定术中管理。在某些病例中，术中FSA有助于避免根治性睾丸切除术。
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