Instituto de Física Aplicada, CSIC, Madrid, Spain.
Talanta. 2011 Sep 15;85(3):1442-7. doi: 10.1016/j.talanta.2011.06.033. Epub 2011 Jun 17.
An array of Love-wave sensors based on quartz and Novolac has been developed to detect chemical warfare agents (CWAs). These weapons are a risk for human health due to their efficiency and high lethality; therefore an early and clear detection is of enormous importance for the people safety. Love-wave devices realized on quartz as piezoelectric substrate and Novolac as guiding layer have been used to make up an array of six sensors, which have been coated with specific polymers by spin coating. The CWAs are very dangerous and for safety reasons their well known simulants have been used: dimethylmethyl phosphonate (DMMP), dipropyleneglycol methyl ether (DPGME), dimethylmethyl acetamide (DMA), dichloroethane (DCE), dichloromethane (DCM) and dichloropentane (DCP). The array has been exposed to these CWA simulants detecting very low concentrations, such as 25 ppb of DMMP, a simulant of nerve agent sarin. Finally, principal component analysis (PCA) as data pre-processing and discrimination technique, and probabilistic neural networks (PNN) as patterns classification technique have been applied. The performance of the sensor array has shown stability, accuracy, high sensitivity and good selectivity to these simulants.
已经开发了一种基于石英和 novolac 的 love 波传感器阵列，用于检测化学战剂 (CWA)。由于这些武器的效率和高杀伤力，它们对人类健康构成了威胁；因此，早期和明确的检测对于人民的安全至关重要。已经使用在石英作为压电基底和 novolac 作为引导层上实现的 love 波器件来制作由六个传感器组成的阵列，这些传感器已经通过旋涂涂覆了特定的聚合物。由于安全原因，CWA 非常危险，因此使用了它们众所周知的模拟物：二甲氧基甲基膦酸酯 (DMMP)、二丙二醇甲醚 (DPGME)、二甲基甲基乙酰胺 (DMA)、二氯乙烷 (DCE)、二氯甲烷 (DCM) 和二氯戊烷 (DCP)。该阵列已经暴露于这些 CWA 模拟物中，检测到非常低的浓度，例如 25ppb 的 DMMP，这是一种神经毒剂沙林的模拟物。最后，应用了主成分分析 (PCA) 作为数据预处理和判别技术，以及概率神经网络 (PNN) 作为模式分类技术。传感器阵列的性能表现出对这些模拟物的稳定性、准确性、高灵敏度和良好选择性。
