Henan Key Laboratory for Environmental Pollution Control, Ministry of Education, School of Chemistry and Environmental Sciences, Henan Normal University, Xinxiang, China.
Talanta. 2011 Sep 15;85(3):1598-602. doi: 10.1016/j.talanta.2011.06.050. Epub 2011 Jun 25.
Present study described a simple, sensitive, and viable method for the determination of bisphenol A, 4-n-nonylphenol and 4-tert-octylphenol in water samples using temperature-controlled ionic liquid dispersive liquid-phase microextraction coupled to high performance liquid chromatography-fluorescence detector. In this experiment, 1-octyl-3-methylimidazolium hexafluorophosphate ([C(8)MIM][PF(6)]) was used as the extraction solvent, and bisphenol A, 4-n-nonylphenol and 4-tert-octylphenol were selected as the model analytes. Parameters affecting the extraction efficiency such as the volume of [C(8)MIM][PF(6)], dissolving temperature, extraction time, sample pH, centrifuging time and salting-out effect have been investigated in detail. Under the optimized conditions, good linear relationship was found in the concentration range of 1.0-100 μg L(-1) for BPA, 1.5-150 μg L(-1) for 4-NP, and 3-300 μg L(-1) for 4-OP, respectively. Limits of detection (LOD, S/N=3) were in the range of 0.23-0.48 μg L(-1). Intra day and inter day precisions (RSDs, n=6) were in the range of 4.6-5.5% and 8.5-13.3%, respectively. This method has been also successfully applied to analyze the real water samples at two different spiked concentrations and excellent results were obtained.
本研究描述了一种使用温控离子液体分散液相微萃取结合高效液相色谱-荧光检测法测定水样中双酚 A、4-壬基酚和 4-叔辛基酚的简单、灵敏、可行的方法。在本实验中，使用 1-辛基-3-甲基咪唑六氟磷酸盐([C(8)MIM][PF(6)])作为萃取溶剂，选择双酚 A、4-壬基酚和 4-叔辛基酚作为模型分析物。详细研究了影响萃取效率的参数，如[C(8)MIM][PF(6)]的体积、溶解温度、萃取时间、样品 pH 值、离心时间和盐析效应。在优化条件下，BPA 的浓度范围为 1.0-100 μg L(-1)，4-NP 的浓度范围为 1.5-150 μg L(-1)，4-OP 的浓度范围为 3-300 μg L(-1)，均呈现良好的线性关系。检测限（LOD，S/N=3）在 0.23-0.48 μg L(-1)范围内。日内和日间精密度（RSD，n=6）分别在 4.6-5.5%和 8.5-13.3%范围内。该方法还成功应用于两种不同加标浓度的实际水样分析，得到了良好的结果。
