Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
JPEN J Parenter Enteral Nutr. 2011 Sep;35(5 Suppl):36S-43S. doi: 10.1177/0148607111413776. Epub 2011 Aug 1.
Two of the most challenging issues in the clinical management of the obese patient are assessing energy requirements and whether hypocaloric (permissive) underfeeding should be employed. Multiple predictive equations have been used in the literature to estimate resting metabolic rate, although no consensus has emerged regarding which prediction equation is most accurate and precise in the obese population. Hypocaloric, or permissive underfeeding, specifically refers to the intentional administration of calories that are less than predicted energy expenditure. Thus far, very few studies performed have been performed to assess the efficacy of hypocaloric feeding in the obese hospitalized patient. It is concluded that the optimal caloric intake of obese patients in the intensive care unit remains unclear given the limitation of the existing data.
肥胖患者临床管理中最具挑战性的两个问题是评估能量需求和是否应采用低热量(允许性)喂养。文献中已经使用了多种预测方程来估计静息代谢率,但对于哪种预测方程在肥胖人群中最准确和精确,尚未达成共识。低热量或允许性喂养是指故意给予低于预测能量消耗的热量。到目前为止,很少有研究评估低热量喂养在肥胖住院患者中的疗效。鉴于现有数据的局限性,得出的结论是,由于现有数据的局限性,肥胖患者在重症监护病房的最佳热量摄入仍不清楚。