Departamento de Epidemiologia, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, SP, Brasil.
Rev Saude Publica. 2011 Oct;45(5):887-96. doi: 10.1590/s0034-89102011005000051. Epub 2011 Jul 29.
To assess the prevalence of chronic obstructive pulmonary disease and related risk factors.
A population-based cross-sectional study with 1,441 individuals of both sexes aged 40 years or more was conducted in the city of São Paulo, Brazil, between 2008 and 2009. A two-stage (census tract, household) cluster random sampling stratified by sex and age was used and data was collected through home interviews. Multiple Poisson regression was used in the adjusted analysis.
Of all respondents, 4.2% (95%CI: 3.1;5.4) reported chronic obstructive pulmonary disease. After adjustment the following factors were found independently associated with self-reported chronic obstructive pulmonary disease: number of cigarettes smoked in their lifetime (>1,500 vs. none) (PR=3.85; 95%CI: 1.87;7.94); easily fatigued (yes vs. no) (PR=2.61; 95%CI: 1.39;4.90); age (60;69 vs. 50;59) (PR 3.27; 95%CI: 1.01;11.24); age (70 and over vs. 50;59) (PR 4.29; 95%CI: 1.30;11.29); health conditions in the last 15 days (yes vs. no) (PR=1.31; 95%CI: 1.02;1.77); leisure-time physical activity (yes vs. no) (PR=0.57; 95%CI: 0.26;0.97).
The prevalence of chronic obstructive pulmonary disease is high in the population studied and is associated with smoking and age over 60. Frequent health conditions and low leisure-time physical activity are a consequence of the disease.
评估慢性阻塞性肺疾病的流行情况和相关危险因素。
本研究为一项基于人群的横断性研究,共纳入巴西圣保罗市 1441 名 40 岁及以上的男性和女性。采用两阶段(居委会、家庭)分层整群随机抽样方法,通过入户访谈收集数据。调整分析采用多泊松回归。
在所有受访者中,4.2%(95%CI:3.1;5.4)报告患有慢性阻塞性肺疾病。调整后,以下因素与自我报告的慢性阻塞性肺疾病独立相关:一生中吸烟的支数(>1500 支与从未吸烟)(PR=3.85;95%CI:1.87;7.94);易疲劳(是与否)(PR=2.61;95%CI:1.39;4.90);年龄(60-69 岁与 50-59 岁)(PR 3.27;95%CI:1.01;11.24);年龄(70 岁及以上与 50-59 岁)(PR 4.29;95%CI:1.30;11.29);过去 15 天健康状况(是与否)(PR=1.31;95%CI:1.02;1.77);闲暇时间体力活动(是与否)(PR=0.57;95%CI:0.26;0.97)。
在所研究的人群中,慢性阻塞性肺疾病的患病率较高,与吸烟和年龄超过 60 岁有关。频繁的健康状况和低水平的闲暇时间体力活动是该疾病的后果。