Svetlichnaya Jana, Klein Liviu
Northwestern University Feinberg School of Medicine, 676 N. St Clair Street, Suite 600, Chicago, IL 60611, USA.
Expert Rev Cardiovasc Ther. 2011 Jul;9(7):903-12. doi: 10.1586/erc.11.89.
Atrial fibrillation and heart failure have been called the twin cardiovascular epidemics of the 21st Century. The prevalence of both conditions is increasing in the elderly and often the two conditions coexist in the same patients, leading to worse outcomes. Current data show that rate control and rhythm control are both reasonable strategies for the treatment of atrial fibrillation in heart failure patients. Emerging data suggest the beneficial effects of novel therapeutic approaches such as cardiac resynchronization therapy, and pulmonary vein isolation on left ventricular remodeling and functional outcomes. Anticoagulation remains a mainstay of therapy for stroke prevention in this high-risk population.
心房颤动和心力衰竭被称为21世纪心血管领域的两大流行疾病。这两种疾病在老年人中的患病率都在上升，而且常常在同一患者中共存，导致更差的预后。目前的数据表明，心率控制和节律控制都是治疗心力衰竭合并心房颤动患者的合理策略。新出现的数据提示了心脏再同步治疗和肺静脉隔离等新型治疗方法对左心室重构和功能结局的有益作用。抗凝治疗仍然是这一高危人群预防卒中的主要治疗手段。
