University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham B18 7QH, UK.
Heart Fail Clin. 2013 Oct;9(4):427-35, viii. doi: 10.1016/j.hfc.2013.07.008.
Heart failure and atrial fibrillation are major problems of modern cardiology with important clinical, prognostic, and socioeconomic implications. The risks are high morbidity, impaired quality of life, poor outcome, and increased risk of stroke. Oral anticoagulation with vitamin K antagonists or novel licensed medicines should be considered unless contraindicated. Possible benefits of sinus rhythm maintenance are not entirely clear and need to be explored further. Relatively scarce data are available on stroke prevention in atrial fibrillation in heart failure with preserved ejection fraction; this requires further research.
心力衰竭和心房颤动是现代心脏病学的主要问题，具有重要的临床、预后和社会经济学意义。这些风险包括高发病率、生活质量受损、预后不良和中风风险增加。除非有禁忌症，否则应考虑使用维生素 K 拮抗剂或新型许可药物进行口服抗凝治疗。维持窦性节律的可能益处尚不完全清楚，需要进一步探讨。心力衰竭伴射血分数保留的心房颤动患者的卒中预防相关数据相对较少，这需要进一步研究。
