正畸器械表面镀银-铂涂层的抗菌效果。
Antibacterial effect of silver-platinum coating for orthodontic appliances.
机构信息
Department of Orthodontics, Dental Science Research Institute, Chonnam National University, Gwangju, Korea.
出版信息
Angle Orthod. 2012 Jan;82(1):151-7. doi: 10.2319/021411-111.1. Epub 2011 Aug 2.
OBJECTIVE
To develop a hard coating for stainless surfaces based on silver (Ag)-platinum (Pt) alloys.
MATERIALS AND METHODS
Ag-Pt alloys, which have high degree of biocompatibility, excellent resistance to sterilization conditions, and antibacterial properties to different bacteria, are associated with long-term antibacterial efficiency. Approximately 1.03-µm to 2.34-µm-thick coatings, as determined by scanning electron microscopy, were deposited on stainless surfaces by the simultaneous vaporization of both metals (Ag and Pt) in an inert argon atmosphere. The coating was done by physical vapor deposition. Microorganisms and eukaryotic culture cells were grown on these surfaces.
RESULTS
The coatings released sufficient Ag ions when immersed in phosphate-buffered saline and showed significant antimicrobial potency against Streptococcus mutans and Aggregatibacter actinomycetemcomitans strains. At the same time, human gingival fibroblast cells were not adversely affected.
CONCLUSION
Ag-Pt coatings on load-bearing orthodontic bracket surfaces can provide suitable antimicrobial activity during active orthodontic treatment.
目的
开发一种基于银（Ag）-铂（Pt）合金的不锈钢表面硬质涂层。
材料与方法
Ag-Pt 合金具有高度的生物相容性、优异的耐灭菌条件性和对多种细菌的抗菌性能，具有长期的抗菌效率。通过在惰性氩气气氛中同时蒸发两种金属（Ag 和 Pt），在不锈钢表面沉积了约 1.03-μm 至 2.34-μm 厚的涂层。涂层通过物理气相沉积完成。将微生物和真核培养细胞种植在这些表面上。
结果
当浸入磷酸盐缓冲盐水中时，涂层释放出足够的 Ag 离子，并对变形链球菌和伴放线放线杆菌菌株表现出显著的抗菌效力。同时，对人牙龈成纤维细胞没有不良影响。
结论
在承重正畸托槽表面的 Ag-Pt 涂层可在正畸治疗过程中提供适当的抗菌活性。
Zotero 插件