Department of Gastrointestinal Surgery, GB Pant Hospital, New Delhi, India.
Dig Surg. 2011;28(4):281-7. doi: 10.1159/000329584. Epub 2011 Jul 29.
Although mortality of Whipple's pancreaticoduodenectomy (WPD) is reduced to <5%, morbidity still remains between 30 and 50%. Pancreaticojejunal anastomosis remains the main cause of morbidity. Blumgart anastomosis using transpancreatic U sutures has been proposed to decrease the leak rate and its associated morbidity. We analyzed the results of Blumgart anastomosis applied in consecutive cases of WPD.
Of 189 patients with periampullary or pancreatic cancer admitted, 100 patients underwent WPD. Except for 2 patients (no duct identified preoperatively), all patients underwent pancreaticojejunostomy by the Blumgart anastomotic technique. The records of 98 patients were analyzed for pancreatic leak and its related complications using the definitions given by the International Study Group for Pancreatic Surgery.
Of 98 patients, 63 were men. The mean operative time was 390 min (270-690 min) and blood loss was 275 ml (100-1,000 ml). Overall mortality was 3.06%. The clinically significant pancreatic anastomotic failure leak was seen in only 7 (7.14%) cases (grade B, n = 4; grade C, n = 3) with one patient requiring relaparotomy due to leak. Only one patient died due to a leak-related complication.
Blumgart pancreaticojejunal anastomosis can be routinely used for reconstruction in WPD. It is a technically simple procedure and is associated with low rates of fistula and its related complications.
尽管 Whipple 胰十二指肠切除术(WPD)的死亡率已降至<5%,但发病率仍在 30%至 50%之间。胰肠吻合术仍然是发病率的主要原因。采用经胰腺 U 缝线的 Blumgart 吻合术已被提出以降低漏液率及其相关发病率。我们分析了连续行 WPD 的患者中 Blumgart 吻合术的结果。
在收治的 189 例壶腹周围或胰腺恶性肿瘤患者中,100 例行 WPD。除 2 例患者(术前未发现胆管)外,所有患者均采用 Blumgart 吻合技术行胰肠吻合术。采用国际胰腺外科研究组给出的定义,分析 98 例患者的胰漏及其相关并发症的记录。
98 例患者中,63 例为男性。手术时间平均为 390 分钟(270-690 分钟),出血量为 275 毫升(100-1000 毫升)。总体死亡率为 3.06%。仅 7 例(7.14%)(B 级 4 例;C 级 3 例)出现临床显著的胰吻合失败漏液,其中 1 例因漏液而再次剖腹手术。仅有 1 例患者因漏液相关并发症而死亡。
Blumgart 胰肠吻合术可常规用于 WPD 的重建。它是一种技术简单的手术,吻合口瘘及其相关并发症的发生率较低。