Nowak Mariusz, Marek Bogdan, Kajdaniuk Dariusz, Siemińska Lucyna, Kos-Kudła Beata, Nowak Katarzyna, Głogowska-Szelag Joanna
Wiad Lek. 2011;64(1):49-55.
The authors present the review of the literature concerning on the diagnostic procedure and current treatment of the dry eye, including anti-inflammatory treatment. To diagnosis of the dry eye syndrome is based on the combination of clinical symptoms and clinical tests. These clinical tests evaluate tear clearance, tear stability, ocular surface integrity, tear osmolarity and conjunctival cytology. Measurement of tear osmolarity might provide a "gold standard" of diagnosis, but a practical tear osmolarity test is not yet widely available. Measurement of tear film instability by means of a TBUT test has good overall accuracy and may be more repeatable than many other diagnostic tests. The first step in managing the disease is to identify the underlying etiology and to try to eliminate it and/or treat it. Inflammation and the interruption of the inflammatory cascade seem to be the main focus in the treatment of dry eye, giving the anti-inflammatory therapy a new critical role.
作者对有关干眼诊断程序和当前治疗方法(包括抗炎治疗)的文献进行了综述。干眼综合征的诊断基于临床症状和临床检查的结合。这些临床检查评估泪液清除、泪液稳定性、眼表完整性、泪液渗透压和结膜细胞学。泪液渗透压测量可能提供诊断的“金标准”,但实用的泪液渗透压测试尚未广泛应用。通过泪膜破裂时间(TBUT)测试测量泪膜稳定性具有良好的总体准确性,并且可能比许多其他诊断测试更具可重复性。治疗该疾病的第一步是确定潜在病因并尝试消除和/或治疗它。炎症以及炎症级联反应的中断似乎是干眼治疗的主要重点,这赋予了抗炎治疗新的关键作用。