中性铀-席夫碱受体在水中的阴离子识别。

Anion recognition in water with use of a neutral uranyl-salophen receptor.

机构信息

Department of Chemistry and IMC-CNR, Università La Sapienza, Piazzale Aldo Moro 5, 00185 Roma, Italy.

出版信息

J Org Chem. 2011 Sep 16;76(18):7569-72. doi: 10.1021/jo201213e. Epub 2011 Aug 22.

DOI:10.1021/jo201213e

Abstract

A new water-soluble uranyl-salophen complex incorporating two glucose units has been synthesized. This neutral derivative shows noteworthy binding affinity for fluoride in water thanks to the Lewis acid-base interaction occurring between the metal and the anion. Such interaction is strong enough to overcome the high hydration enthalpy of fluoride. Moreover this complex effectively binds hydrogen phosphate and exhibits remarkably strong association for nucleotide polyanions ADP(3-) and ATP(4-).

摘要

一种新的水溶性铀-水杨醛配合物，其中包含两个葡萄糖单元，已经被合成。由于金属和阴离子之间发生的路易斯酸碱相互作用，这种中性衍生物在水中对氟化物表现出显著的结合亲和力。这种相互作用足够强大，可以克服氟化物的高水合焓。此外，该配合物还能有效地结合磷酸氢盐，并对核苷酸多阴离子 ADP(3-)和 ATP(4-)表现出极强的缔合作用。