Iarovoĭ S K, Shimanovskiĭ N L, Kareva E N
Urologiia. 2011 Mar-Apr(2):67-73.
The article analyses the most typical clinical situations in empirical treatment of pyelonephritis including situations with comorbid severe diseases: decompensated diabetes mellitus, chronic renal failure, HIV-infection. Choice of antibacterial medicines for empiric treatment of pyelonephritis is based on the results of the latest studies of antibioticoresistance of pyelonephritis pathogens as well as on specific features of pharmacokinetics and pharmacodynamics of antibacterial drugs.
本文分析了肾盂肾炎经验性治疗中最典型的临床情况,包括伴有严重合并症的情况:失代偿性糖尿病、慢性肾衰竭、HIV感染。肾盂肾炎经验性治疗抗菌药物的选择基于肾盂肾炎病原体抗生素耐药性的最新研究结果以及抗菌药物的药代动力学和药效学特性。