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[阑尾上皮性肿瘤:近期有哪些变化?]

[Epithelial neoplasia of the appendix: what has recently changed?].

作者信息

Mantziari S, Grass F, Demartines N, Schaefer M

机构信息

Service de chirurgie viscérale, Département de chirurgie, CHUV, Lausanne.

出版信息

Rev Med Suisse. 2011 Jun 22;7(300):1362-5.

PMID:21815537
Abstract

Appendicular tumors are mostly found incidentally in up to 1.5% of all appendectomies. Neuroendocrine tumors are the commonest malignancies, and are associated with an excellent long-term prognosis. While small lesions located at the appendicular tip can be treated with simple appendectomy, advanced tumors require right hemicolectomy. Goblet cell carcinoids are rare tumors showing a mixed phenotype. Long-term outcome is impaired, and for most cases a right hemicolectomy is mandatory. Colonic-type adenocarcinomas have a similar behavior like conventional colonic cancer and should be treated similarly. Mucinous neoplasias possess the characteristic of extensive mucin production with intraperitoneal spread. Treatment options are ranging from right hemicolectomy to multivisceral resection with intraperitoneal chemotherapy.

摘要

阑尾肿瘤在所有阑尾切除术中的偶然发现率高达1.5%。神经内分泌肿瘤是最常见的恶性肿瘤,且预后良好。位于阑尾尖端的小病变可通过单纯阑尾切除术治疗,而晚期肿瘤则需要行右半结肠切除术。杯状细胞类癌是罕见的具有混合表型的肿瘤。其长期预后较差,大多数病例必须行右半结肠切除术。结肠型腺癌的行为与传统结肠癌相似,治疗方式也应类似。黏液性肿瘤具有大量黏液生成并伴有腹膜内播散的特征。治疗选择范围从右半结肠切除术到多脏器切除并联合腹膜内化疗。

相似文献

1
[Epithelial neoplasia of the appendix: what has recently changed?].[阑尾上皮性肿瘤:近期有哪些变化?]
Rev Med Suisse. 2011 Jun 22;7(300):1362-5.
2
Neuroendocrine tumours (carcinoids) of the appendix.阑尾神经内分泌肿瘤(类癌)
Best Pract Res Clin Gastroenterol. 2005 Oct;19(5):729-38. doi: 10.1016/j.bpg.2005.06.003.
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Combined classical carcinoid and goblet cell carcinoid tumor: a new morphologic variant of carcinoid tumor of the appendix.阑尾类癌的一种新形态学变异型:经典类癌与杯状细胞类癌的联合肿瘤。
Am J Surg Pathol. 2010 Aug;34(8):1163-7. doi: 10.1097/PAS.0b013e3181e52916.
4
[Neuroendocrine tumours of the appendix].[阑尾神经内分泌肿瘤]
Vnitr Lek. 2009 Nov;55(11):1051-5.
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Carcinoid tumour of the appendix: problems of diagnosis and treatment.阑尾类癌肿瘤:诊断与治疗问题
Chirurgia (Bucur). 2011 Mar-Apr;106(2):239-45.
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[Appendiceal tumors found at appendectomy].[阑尾切除术中发现的阑尾肿瘤]
J Chir (Paris). 2009 Oct;146 Spec No 1:36-8. doi: 10.1016/j.jchir.2009.08.006. Epub 2009 Oct 28.
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Primary appendiceal carcinoma--epidemiology, surgery and survival: results of a German multi-center study.原发性阑尾癌——流行病学、手术和生存:德国多中心研究的结果。
Eur J Surg Oncol. 2010 Aug;36(8):763-71. doi: 10.1016/j.ejso.2010.05.025. Epub 2010 Jun 18.
8
Carcinoid tumors of the appendix. Prognostic factors and evaluation of indications for right hemicolectomy.阑尾类癌肿瘤。预后因素及右半结肠切除术适应证的评估
Hepatogastroenterology. 2005 Jan-Feb;52(61):123-7.
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[Primary malignant tumors of the vermiform appendix: clinico-pathologic study of 8 cases].[阑尾原发性恶性肿瘤:8例临床病理研究]
Arq Gastroenterol. 1979 Apr-Jun;16(2):62-6.
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[Carcinoid tumor of the appendix. A not especially rare entity].[阑尾类癌肿瘤。一种并非特别罕见的实体]
Minerva Chir. 1999 Mar;54(3):175-8.

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