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TET1 functions as a tumor suppressor in lung adenocarcinoma through epigenetic remodeling and immune modulation.
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Ten-Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy.
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Stage-specific DNA methylation dynamics in mammalian heart development.
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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain.
Cell. 2011 Apr 29;145(3):423-34. doi: 10.1016/j.cell.2011.03.022. Epub 2011 Apr 14.
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TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Nature. 2011 May 19;473(7347):343-8. doi: 10.1038/nature10066. Epub 2011 Apr 13.
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Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
Nature. 2011 May 19;473(7347):398-402. doi: 10.1038/nature10008. Epub 2011 Apr 3.
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Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.
Nature. 2011 May 19;473(7347):389-93. doi: 10.1038/nature09934. Epub 2011 Mar 30.
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Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine.
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Active DNA demethylation: many roads lead to Rome.
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Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway.
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