Henderson J M
Department of Surgery, Emory University School of Medicine, Atlanta, Georgia.
Surg Clin North Am. 1990 Apr;70(2):405-23. doi: 10.1016/s0039-6109(16)45089-9.
Distal splenorenal shunt (DSRS) provides selective decompression of gastroesophageal varices, with maintenance of portal hypertension and prograde portal flow to the cirrhotic liver. Accurate patient evaluation is essential to select appropriate patients for DSRS. Variceal bleeding control is greater than 85% and is as effective as total portosystemic shunts. Maintenance of prograde portal flow is greater than 90% in nonalcoholic disease, but only 50% in alcoholic cirrhosis; the latter is improved by total splenopancreatic disconnection. Hepatic function is better maintained when portal flow is maintained. Encephalopathy is lower after DSRS than after total shunts. Survival is not significantly improved after DSRS in patients with alcoholic cirrhosis compared to outcome after total shunts. The survival in patients with nonalcoholic disease is significantly improved over that of alcoholics.
远端脾肾分流术(DSRS)可选择性地降低胃食管静脉曲张压力,同时维持门静脉高压及向肝硬化肝脏的门静脉正向血流。准确评估患者对于选择合适的DSRS患者至关重要。曲张静脉出血控制率超过85%,与完全门体分流术效果相当。在非酒精性疾病中,门静脉正向血流维持率超过90%,但在酒精性肝硬化中仅为50%;全胰脾离断术可改善后者情况。维持门静脉血流时,肝功能能得到更好的维持。DSRS术后肝性脑病发生率低于完全分流术后。与完全分流术后相比,酒精性肝硬化患者DSRS术后生存率无显著提高。非酒精性疾病患者的生存率明显高于酒精性疾病患者。