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选择性远端脾肾分流术治疗小儿门静脉高压症顽固性静脉曲张出血

Selective distal splenorenal shunts for intractable variceal bleeding in pediatric portal hypertension.

作者信息

Evans S, Stovroff M, Heiss K, Ricketts R

机构信息

Department of Surgery, School of Medicine, Emory University, Atlanta, GA 30322, USA.

出版信息

J Pediatr Surg. 1995 Aug;30(8):1115-8. doi: 10.1016/0022-3468(95)90000-4.

DOI:10.1016/0022-3468(95)90000-4
PMID:7472961
Abstract

The treatment of portal hypertension in the pediatric population has undergone an evolution toward less invasive methods of care. With the advent of endoscopic sclerotherapy, surgery is less common in the acute care of these patients. Few reports deal with the role of portosystemic shunting in the emergent management of variceal hemorrhage in children. To address this issue, the authors studied the medical records of all pediatric patients at their institution who underwent placement of a shunt for portal hypertension during the last 10 years. Nine patients underwent a total of 10 emergent or semiurgent shunting procedures. Seven were boys and two were girls. Six patients had portal hypertension as a result of intrahepatic disease. Two had extrahepatic portal vein thrombosis. Five children had abnormal hepatic function. The median age at the time of the procedure was 9 years. The indication for surgical shunting in all cases was gastrointestinal hemorrhage not responsive to sclerotherapy. Eight patients underwent emergent distal splenorenal shunts (DSRS), and two underwent a nonselective mesocaval shunt, with one undergoing both. Postoperatively all patients had cessation of bleeding. Operative mortality was zero. Early complications included ascites (3), small bowel obstruction (1), and hepatorenal syndrome (1). The child who underwent a nonselective shunt procedure had encephalopathy. Two DSRS thrombosed, requiring reexploration; eight shunts remained patent. Three patients eventually had orthotopic liver transplantation (OLT) because of progressive hepatic failure. Two children died; neither death was shunt related.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

儿童门静脉高压症的治疗已朝着侵入性较小的护理方法发展。随着内镜硬化疗法的出现,手术在这些患者的急性护理中已不那么常见。很少有报告涉及门体分流术在儿童静脉曲张出血紧急处理中的作用。为解决这一问题,作者研究了他们机构中过去10年接受门静脉高压分流术的所有儿科患者的病历。9名患者共接受了10次紧急或半紧急分流手术。7名是男孩,2名是女孩。6名患者因肝内疾病导致门静脉高压。2名患者有肝外门静脉血栓形成。5名儿童肝功能异常。手术时的中位年龄为9岁。所有病例中手术分流的指征是对硬化疗法无反应的胃肠道出血。8名患者接受了紧急远端脾肾分流术(DSRS),2名患者接受了非选择性肠系膜上腔静脉分流术,其中1名患者接受了两种手术。术后所有患者出血停止。手术死亡率为零。早期并发症包括腹水(3例)、小肠梗阻(1例)和肝肾综合征(1例)。接受非选择性分流手术的儿童出现了脑病。2例DSRS血栓形成,需要再次手术探查;8个分流仍保持通畅。3名患者最终因进行性肝功能衰竭接受了原位肝移植(OLT)。2名儿童死亡;均与分流无关。(摘要截断于250字)

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