Kjaergaard B, Walter S, Knudsen A, Johansen B, Barlebo H
Aalborg Sygehus, urologisk afdeling, gynaekologisk afdeling og patologisk institut.
Ugeskr Laeger. 1990 Mar 5;152(10):658-9.
Twenty-three postmenopausal women with recurrent cystitis were allorted at random to treatment for five months with local oestrogen in the vagina or placebo treatment with the object of assessing the local effect on the vaginal epithelium and on the tendency to recurrent cystitis. The therapeutic group and the placebo group were entirely comparable prior to treatment. In the therapeutic group, the oestrogen index in vaginal scrapings was significantly higher after treatment than in the placebo group (p less than 0.01). The number of positive urine cultures and the patients/satisfaction with treatment wee not significantly different in the two groups.
23名复发性膀胱炎的绝经后女性被随机分配，分别接受为期五个月的阴道局部雌激素治疗或安慰剂治疗，目的是评估其对阴道上皮的局部影响以及对复发性膀胱炎发病倾向的影响。治疗组和安慰剂组在治疗前完全具有可比性。治疗组治疗后阴道刮片中的雌激素指数显著高于安慰剂组（p<0.01）。两组的尿培养阳性数及患者对治疗的满意度无显著差异。
