Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan.
Org Lett. 2011 Sep 2;13(17):4570-3. doi: 10.1021/ol2017627. Epub 2011 Aug 5.
6-O-Modified β-cyclodextrins, such as heptakis(6-O-triisopropylsilyl)-β-cyclodextrin (TIPS-β-CD) and heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin (TBDMS-β-CD), formed 2:1 inclusion complexes with pyrene in benzene and cyclohexane with high association constants. The X-ray crystalline structure of the TIPS-β-CD-pyrene complex obtained from the benzene solution showed that one pyrene molecule was incorporated in the form of a sandwich-type complex with two benzene molecules within the cavity of the dimer formed by two TIPS-β-CD molecules.
6-O-修饰的β-环糊精，如七（6-O-三异丙基硅基）-β-环糊精（TIPS-β-CD）和七（6-O-叔丁基二甲基硅基）-β-环糊精（TBDMS-β-CD），在苯和环己烷中与芘形成 2:1 的包合络合物，具有高的结合常数。从苯溶液中得到的 TIPS-β-CD-芘络合物的 X 射线晶体结构表明，一个芘分子以夹心型络合物的形式与两个苯分子一起被包含在由两个 TIPS-β-CD 分子形成的二聚体的腔内。
