Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Gastrointest Endosc. 2011 Oct;74(4):916-20. doi: 10.1016/j.gie.2011.05.050. Epub 2011 Aug 6.
Most benign biliary strictures nowadays are managed endoscopically with plastic stents or with a insertion of a fully covered self-expandable metal stent (fcSEMS). The paradigm for the treatment of benign hilar strictures precludes the use of an fcSEMS because it obstructs the intrahepatic bile ducts, in particular, the contralateral hepatic duct. It is unknown whether use of a plastic stent in the opposite hepatic duct after deployment of an fcSEMS across the liver hilum provides an adequate solution for this problem.
To evaluate the use of an fcSEMS in combination with a contralateral plastic stent in the treatment of benign hilar strictures.
Case series.
Tertiary referral hospital.
Two consecutive patients with benign hilar strictures.
Placement of an intrahepatically deployed fcSEMS in conjunction with a contralateral 10F plastic stent for 4 to 5 months followed by stent removal and cholangiogram.
Clinical and laboratory follow-up of at least 9 months.
In both patients, the indwelling period of the stents was uneventful as was stent removal. Both strictures resolved, and there were no clinical or biochemical signs of a recurrent stricture.
Small number of patients.
Treatment of benign hilar strictures with an fcSEMS deployed across the liver hilum in conjunction with a contralateral plastic stent placement is feasible without ensuing cholangitis caused by bile duct occlusion.
目前,大多数良性胆道狭窄都是通过内镜下放置塑料支架或完全覆膜自膨式金属支架(fcSEMS)来治疗。由于 fcSEMS 会阻塞肝内胆管,特别是对侧肝管,因此不适合用于治疗良性肝门部狭窄。尚不清楚在 fcSEMS 穿过肝门后,在对侧肝管内放置塑料支架是否能为解决这一问题提供充分的解决方案。
评估 fcSEMS 联合对侧塑料支架在治疗良性肝门部狭窄中的应用。
病例系列研究。
三级转诊医院。
两名连续的良性肝门部狭窄患者。
在肝内放置 fcSEMS,并在 4 至 5 个月后放置对侧 10F 塑料支架,随后取出支架并进行胆管造影。
至少 9 个月的临床和实验室随访。
两名患者的支架留置期均无不良事件,支架取出也很顺利。两处狭窄均得到缓解,且无狭窄复发的临床或生化迹象。
患者数量较少。
fcSEMS 穿过肝门放置联合对侧塑料支架置入治疗良性肝门部狭窄是可行的,不会因胆管阻塞而导致胆管炎。