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突破障碍:使用可提取的全覆膜金属支架治疗良性肝门胆管狭窄。

Breaking the barrier: using extractable fully covered metal stents to treat benign biliary hilar strictures.

机构信息

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.

出版信息

Gastrointest Endosc. 2011 Oct;74(4):916-20. doi: 10.1016/j.gie.2011.05.050. Epub 2011 Aug 6.

Abstract

BACKGROUND

Most benign biliary strictures nowadays are managed endoscopically with plastic stents or with a insertion of a fully covered self-expandable metal stent (fcSEMS). The paradigm for the treatment of benign hilar strictures precludes the use of an fcSEMS because it obstructs the intrahepatic bile ducts, in particular, the contralateral hepatic duct. It is unknown whether use of a plastic stent in the opposite hepatic duct after deployment of an fcSEMS across the liver hilum provides an adequate solution for this problem.

OBJECTIVE

To evaluate the use of an fcSEMS in combination with a contralateral plastic stent in the treatment of benign hilar strictures.

DESIGN

Case series.

SETTING

Tertiary referral hospital.

PATIENTS

Two consecutive patients with benign hilar strictures.

INTERVENTIONS

Placement of an intrahepatically deployed fcSEMS in conjunction with a contralateral 10F plastic stent for 4 to 5 months followed by stent removal and cholangiogram.

MAIN OUTCOME MEASUREMENTS

Clinical and laboratory follow-up of at least 9 months.

RESULTS

In both patients, the indwelling period of the stents was uneventful as was stent removal. Both strictures resolved, and there were no clinical or biochemical signs of a recurrent stricture.

LIMITATIONS

Small number of patients.

CONCLUSIONS

Treatment of benign hilar strictures with an fcSEMS deployed across the liver hilum in conjunction with a contralateral plastic stent placement is feasible without ensuing cholangitis caused by bile duct occlusion.

摘要

背景

目前,大多数良性胆道狭窄都是通过内镜下放置塑料支架或完全覆膜自膨式金属支架(fcSEMS)来治疗。由于 fcSEMS 会阻塞肝内胆管,特别是对侧肝管,因此不适合用于治疗良性肝门部狭窄。尚不清楚在 fcSEMS 穿过肝门后,在对侧肝管内放置塑料支架是否能为解决这一问题提供充分的解决方案。

目的

评估 fcSEMS 联合对侧塑料支架在治疗良性肝门部狭窄中的应用。

设计

病例系列研究。

设置

三级转诊医院。

患者

两名连续的良性肝门部狭窄患者。

干预措施

在肝内放置 fcSEMS,并在 4 至 5 个月后放置对侧 10F 塑料支架,随后取出支架并进行胆管造影。

主要观察指标

至少 9 个月的临床和实验室随访。

结果

两名患者的支架留置期均无不良事件,支架取出也很顺利。两处狭窄均得到缓解,且无狭窄复发的临床或生化迹象。

局限性

患者数量较少。

结论

fcSEMS 穿过肝门放置联合对侧塑料支架置入治疗良性肝门部狭窄是可行的,不会因胆管阻塞而导致胆管炎。

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