Department of Plastic Surgery, Helsinki University Hospital, Helsinki, Finland.
Burns. 2011 Nov;37(7):1140-4. doi: 10.1016/j.burns.2011.07.002. Epub 2011 Aug 6.
The purpose of this study was to investigate the prevalence of adrenal haemorrhage (AH) in non-surviving patients with severe burns by combining the clinical notes and autopsy data.
A retrospective review of all adult (age >18 years) burn patients who died in the Helsinki Burn Centre, Helsinki, Finland during 1.1.1995 to 31.12.2005 was conducted. Patients diagnosed with AH either in the clinical charts or in the autopsy reports were sorted out. Special attention was paid to the course of events preceding death and autopsy findings.
We identified four patients, creating a prevalence of 5.6%. None of the patients was diagnosed with AH alive. Three patients we diagnosed with bilateral AH, all young men. Cause of death was multiple organ failure (MOF) in all three cases. On the autopsy, they were diagnosed with 5±1 organ failures. One case of unilateral AH was established, an elderly male with hot air sauna burns. Clinical charts and autopsy data suggest idiopathic AH.
The prevalence of AH is higher than previously estimated in non-surviving patients with burns. Bilateral AH occurred later then 1 week after the burn trauma. Bilateral AH always presented with sepsis, multiple organ failure and acute renal failure.
本研究旨在通过结合临床病历和尸检资料，调查非存活严重烧伤患者中肾上腺出血（AH）的发生率。
对 1995 年 1 月 1 日至 2005 年 12 月 31 日期间在芬兰赫尔辛基烧伤中心死亡的所有成年（年龄>18 岁）烧伤患者进行回顾性分析。从临床病历或尸检报告中筛选出诊断为 AH 的患者。特别注意死亡前的病程和尸检结果。
我们确定了 4 例患者，患病率为 5.6%。没有患者在活着时被诊断为 AH。3 例患者被诊断为双侧 AH，均为年轻男性。3 例患者的死因均为多器官功能衰竭（MOF）。在尸检中，他们被诊断为 5±1 个器官衰竭。1 例单侧 AH 患者为老年男性，被热空气桑拿烧伤。临床病历和尸检资料提示为特发性 AH。
在非存活烧伤患者中，AH 的患病率高于以往估计。双侧 AH 发生在烧伤后 1 周以后。双侧 AH 总是伴有脓毒症、多器官功能衰竭和急性肾功能衰竭。
Zotero 插件