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橙皮素经膳食摄入后在大鼠体内的组织分布。

Tissue distribution of hesperetin in rats after a dietary intake.

作者信息

Takumi Hiroko, Mukai Rie, Ishiduka Sawako, Kometani Takashi, Terao Junji

机构信息

Institute of Health Sciences, Ezaki Glico Co., Ltd., Nishiyodogawa-ku, Osaka, Japan.

出版信息

Biosci Biotechnol Biochem. 2011;75(8):1608-10. doi: 10.1271/bbb.110157. Epub 2011 Aug 7.

DOI:10.1271/bbb.110157
PMID:21821945
Abstract

Hesperetin, the aglycone of hesperidin present in citrus fruits, possesses various biological activities. We assessed the tissue distribution of hesperetin in rats fed with a 0.2% hesperetin diet for 4 weeks. Its highest concentration was found in the liver, and the second highest was in the aorta. The aorta is assumed to be one of the main target tissues of hesperetin for exerting its functions.

摘要

橙皮素是柑橘类水果中橙皮苷的苷元,具有多种生物活性。我们评估了给大鼠喂食0.2%橙皮素饮食4周后橙皮素在大鼠体内的组织分布情况。发现其在肝脏中的浓度最高,其次是在主动脉中。主动脉被认为是橙皮素发挥其功能的主要靶组织之一。

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