Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi.
Metab Syndr Relat Disord. 2011 Dec;9(6):461-7. doi: 10.1089/met.2011.0033. Epub 2011 Aug 8.
The metabolic syndrome is an important cluster of coronary heart disease risk factors with common insulin resistance. Although the prevalence of metabolic syndrome is high among Asians, including Indians, no sizeable literature is available about the magnitude of metabolic syndrome in rural areas, especially in women.
Blood pressure and anthropometric measurements were noted in 307 women, aged ≥20 years, selected through a multistage sampling technique. Blood samples were collected after overnight fasting and subjected to biochemical quantification such as fasting blood glucose, triglycerides, and high-density lipoprotein cholesterol (HDL-C). Data were analyzed using updated National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) definition by modifying the waist circumference cutoffs as per Asia-Pacific guidelines.
Overall metabolic syndrome was observed in 12.0% [95% confidence interval (CI); 8.5-16.8] of the rural women population. Women in the age group ≥60 years had the highest prevalence (27.8%), whereas those in the age group 20-39 years had the lowest prevalence (4.2%). At least one component of metabolic syndrome was present in nearly 95% of the study respondents; 41.6% had at least two, 12.0% had at least three, and 2.6% had at least four components of metabolic syndrome. None of the participants had all the five components.
The current prevalence of metabolic syndrome in women in rural communities of the selected area, although less than that in their urban counterparts, could be a serious problem in the future. It is incumbent on government agencies and the medical community to address this issue to prevent the consequences of its increased burden.
代谢综合征是一组重要的冠心病危险因素，其共同特征为胰岛素抵抗。尽管亚洲人（包括印度人）的代谢综合征患病率较高，但关于农村地区（尤其是女性）代谢综合征的大量文献尚不多见。
采用多阶段抽样技术，选择了 307 名年龄≥20 岁的女性，记录其血压和人体测量值。采集隔夜空腹血样，进行生化定量检测，包括空腹血糖、甘油三酯和高密度脂蛋白胆固醇（HDL-C）。采用经亚太指南修正的腰围切点更新后的美国国家胆固醇教育计划成人治疗专家组第三次报告（NCEP ATP III）定义对数据进行分析。
农村女性人群中代谢综合征总患病率为 12.0%（95%可信区间为 8.5%-16.8%）。≥60 岁年龄组的女性患病率最高（27.8%），而 20-39 岁年龄组的女性患病率最低（4.2%）。几乎所有研究对象都存在至少一种代谢综合征组分，其中 41.6%存在至少两种组分，12.0%存在至少三种组分，2.6%存在至少四种组分。没有任何一位参与者存在所有五种组分。
在所选择地区农村社区女性中，目前代谢综合征的患病率虽然低于城市女性，但未来可能成为一个严重问题。政府机构和医疗界有责任解决这一问题，以防止其负担增加带来的后果。
