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特发性鸟枪弹样脉络膜视网膜病变的玻璃体内视网膜手术治疗。

Pars plana vitrectomy for vitreo-retinal complications of birdshot chorioretinopathy.

机构信息

Institut Clínic d'Oftalmologia, Hospital Clínic de Barcelona, Barcelona, Spain.

出版信息

Ocul Immunol Inflamm. 2011 Oct;19(5):346-52. doi: 10.3109/09273948.2011.590265. Epub 2011 Aug 8.

Abstract

PURPOSE

To evaluate the anatomical and functional outcomes of pars plana vitrectomy (PPV) in the treatment of vitreoretinal complications of birdshot chorioretinopathy (BCR).

METHODS

The clinical records of 9 consecutive patients (16 eyes) with vitreo retinal complications in BCR refractory to medical therapy who underwent pars plana vitrectomy were reviewed.

RESULTS

Indications for PPV were macular edema in 9 eyes (56.2%), and persistent vitreous opacities in 7 (43.8%). At a mean postoperative follow-up of 44.1 months, best-corrected visual acuity improved ≥2 Snellen lines in 9 eyes (56.2%), remained stable in 6 (37.5%) and worsened in 1 eye (11.1%). Systemic medication was significatively reduced after surgery (p = .020) and macular thickness on optical coherence tomography exams decreased significatively in eyes with macular edema (p= .0039).

CONCLUSIONS

In this small series of eyes with limited follow-up PPV seems to be a safe and effective for treatment of vitreoretinal complications in patients with BCR.

摘要

目的

评估经睫状体平坦部玻璃体切除术(PPV)治疗鸟枪弹样脉络膜视网膜病变(BCR)的玻璃体视网膜并发症的解剖和功能结果。

方法

回顾性分析了 9 例(16 只眼)经药物治疗无效的 BCR 合并玻璃体视网膜并发症患者行睫状体平坦部玻璃体切除术的临床资料。

结果

9 只眼(56.2%)的手术指征为黄斑水肿,7 只眼(43.8%)为持续的玻璃体混浊。平均随访 44.1 个月后,9 只眼(56.2%)最佳矫正视力提高≥2 行 Snellen 视力表,6 只眼(37.5%)保持稳定,1 只眼(11.1%)恶化。术后全身用药明显减少(p=0.020),黄斑水肿眼的光学相干断层扫描检查黄斑厚度明显降低(p=0.0039)。

结论

在这项小系列研究中,有限随访的情况下,PPV 似乎是治疗 BCR 患者玻璃体视网膜并发症的一种安全有效的方法。

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