Department of Colon & Rectal Surgery, University of Ulsan College of Medicine and Asan Medical Center, 388-1 Poongnap-2-Dong, Songpa-Ku, Seoul 138-736, Korea.
Am J Surg. 2011 Nov;202(5):e48-51. doi: 10.1016/j.amjsurg.2010.09.020. Epub 2011 Aug 6.
Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare disease of unclear origin and pathophysiology. Treatment is symptomatic, with no particular medical therapy except for corticosteroids. We describe a patient with steroid-refractory CMUSE. A 25-year-old woman underwent bowel surgery 4 times because of small-bowel obstruction. She was diagnosed with CMUSE. Despite steroid treatment and immunosuppressive therapy, she continued to complain of recurrent gastrointestinal symptoms and persistent anemia. To avoid short-bowel syndrome in our patient, new medical treatment is necessary for steroid-refractory CMUSE.
不明原因多灶性溃疡性狭窄性肠炎（CMUSE）是一种病因和病理生理学尚不清楚的罕见疾病。治疗方法是对症治疗，除了皮质类固醇外，没有特别的医学治疗方法。我们描述了一例类固醇难治性 CMUSE 患者。一名 25 岁女性因小肠梗阻接受了 4 次肠道手术。她被诊断为 CMUSE。尽管接受了类固醇治疗和免疫抑制治疗，但她仍持续抱怨反复出现的胃肠道症状和持续的贫血。为了避免我们的患者出现短肠综合征，对于类固醇难治性 CMUSE 需要新的药物治疗。
