Lulu B A, Lutz W, Stea B, Cetas T C
Department of Radiation Oncology, University of Arizona, Tucson 85724.
Int J Radiat Oncol Biol Phys. 1990 Apr;18(4):951-5. doi: 10.1016/0360-3016(90)90422-g.
We have initiated a Phase I clinical trial of interstitial hyperthermia induced with inductively heated ferromagnetic implants in combination with Ir-192 implants for glioblastomas and anaplastic astrocytomas of the brain. For speed and accuracy of the implant procedure, and to control the radiation and thermal dose, a stereotaxic frame is used to position a template. We have modified the Brown-Roberts-Wells frame to be used with a variety of templates which we designed. On the morning of the implant procedure, a CT scan is done, and a CT-based treatment plan is then completed before the patient goes to the operating room. We also describe the CT-based treatment planning system developed to accommodate the template-guided implant and illustrate its clinical use.
