University of Mississippi Medical Center, Jackson, 39216, USA.
Am J Med Sci. 2011 Dec;342(6):535-8. doi: 10.1097/MAJ.0b013e31822c0933.
This case report describes a patient who developed rhabdomyolysis temporally associated with the use of a mislabeled acai berry dietary supplement.
The authors describe a 22-year-old man presenting with rhabdomyolysis approximately 2 weeks after starting a weight-loss dietary supplement. His medical history was significant only for hypertension treated with amlodipine. The diagnosis of rhabdomyolysis was confirmed (creatine kinase, 84,000 IU/L, positive urine myoglobin) with other potential causes ruled out. The signs and symptoms of the patient gradually resolved and he was discharged on hospital day 5. Assessment using the Naranjo Adverse Drug Reaction Probability Scale yielded a score of 3, indicating a possible relationship between the supplement and rhabdomyolysis. Although the product was labeled and promoted as containing acai berry and additional ingredients, there was no acai berry found on analysis.
Clinicians should be aware that all dietary supplements may vary in uniformity and contain unknown contaminants.
本病例报告描述了一位患者,他在使用一种标签错误的巴西莓膳食补充剂后出现横纹肌溶解症。
作者描述了一位 22 岁的男性,在开始服用一种减肥膳食补充剂约 2 周后出现横纹肌溶解症。他的病史仅包括用氨氯地平治疗的高血压。横纹肌溶解症的诊断(肌酸激酶,84000IU/L,尿肌红蛋白阳性)得到了确认,排除了其他潜在原因。患者的症状和体征逐渐缓解,他在住院第 5 天出院。使用 Naranjo 药物不良反应概率量表评估得到 3 分,表明补充剂与横纹肌溶解症之间可能存在关联。尽管该产品被标记并宣传为含有巴西莓和其他成分,但分析并未发现巴西莓。
临床医生应注意,所有膳食补充剂可能在均一性方面存在差异,并含有未知的污染物。