Department of Medicine, Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, 645 N. Michigan Avenue, Chicago, IL 60611, USA.
J Acquir Immune Defic Syndr. 2011 Oct 1;58(2):193-7. doi: 10.1097/QAI.0b013e31822d7564.
We sought to describe virologic and clinical retention outcomes among a group of HIV-infected adolescents and young adults (AYA) newly established in an adult HIV clinic compared with matched HIV-infected adults. AYA demonstrated lower rates of HIV-1 virologic suppression and higher rates of HIV-1 viral rebound and loss to follow-up compared with adults. African American AYA had the lowest rates of virologic suppression and the highest rates of viral rebound. Adult providers should consider HIV-infected AYA, particularly African American HIV-infected AYA, to potentially be at high risk for poor clinical outcomes in adult care.
我们旨在描述一组新近进入成人 HIV 诊所的 HIV 感染青少年和年轻成年人（AYA）与匹配的成人 HIV 感染者在病毒学和临床保留方面的结果。与成人相比，AYA 表现出较低的 HIV-1 病毒学抑制率，以及更高的 HIV-1 病毒反弹和失访率。非裔美国 AYA 的病毒学抑制率最低，病毒反弹率最高。成人提供者应考虑将 HIV 感染的 AYA，特别是感染 HIV 的非裔美国 AYA，视为在成人护理中可能面临不良临床结局的高危人群。
