Pediatric Renal Center, University Children's Hospitals UMC Utrecht and AMC Amsterdam, The Netherlands.
Neurourol Urodyn. 2011 Nov;30(8):1576-9. doi: 10.1002/nau.21152. Epub 2011 Aug 8.
This study was conducted to try to objectify assessment of pediatric uroflowmetry curves.
Nine professionals in pediatric incontinence care judged 480 pediatric uroflows. On a 1-5 scale, where 1 = anomalous and 5 = normal, uroflows were assessed on four items: staccato, interrupted, flow time and obstruction. Eighty uroflows were re-evaluated for intra-observer agreement. After staccato and interrupted flow had been defined more sharply, another 100 uroflows were analyzed. Cohen's Kappa test for nominally classified data was applied to assess agreement. Kappa value of <0.20 denoted poor agreement, 0.21-0.40 fair, 0.41-0.60 moderate, 0.61-0.80 substantial and 0.81-1.0 perfect or almost perfect agreement. A second analysis was done using a 3 point scale, anomalous, intermediate and normal.
For interobserver agreement, Kappas were 0.45 for staccato flow, 0.67 for interrupted, 0.59 for flow time, and 0.66 for obstruction. For intra-observer agreement, Kappas were 0.47 for staccato, 0.65 for interrupted, 0.55 for flow time, and 0.65 for obstruction. On a three-point scale, anomalous, intermediate, and normal, interobserver agreement was equal to 0.80 or above. In the second 100 uroflows, the interobserver agreement Kappas were 0.44 for staccato, 0.95 for interrupted, 0.71 for flow time and 0.73 for obstruction.
Moderate to substantial agreement on uroflowmetry curves can be reached, except for staccato. Agreement increases if staccato and interrupted flows are defined more sharply. Staccato is defined as three or more peaks and troughs of more than the square root of maximal flow without touching 0, whereas interrupted flow needs at least one 0 passage. In a normal, uninterrupted uroflow, flow time is under 15 sec.
本研究旨在尝试客观评估小儿尿流率曲线。
9 名小儿尿失禁护理专业人员对 480 例小儿尿流率进行评估。使用 1-5 分制,其中 1 分表示异常,5 分表示正常,评估 4 项内容:中断、停顿、尿流时间和梗阻。80 例尿流率进行了观察者内一致性重评估。在更精确地定义了停顿和中断的流动后,又分析了 100 例尿流率。应用名义分类数据的 Cohen Kappa 检验评估一致性。Kappa 值<0.20 表示一致性差,0.21-0.40 表示一致性一般,0.41-0.60 表示一致性中等,0.61-0.80 表示一致性较好,0.81-1.0 表示一致性极好或几乎完全一致。使用 3 分制(异常、中间、正常)进行了第二次分析。
对于观察者间一致性,停顿的 Kappa 值为 0.45,中断的 Kappa 值为 0.67,尿流时间的 Kappa 值为 0.59,梗阻的 Kappa 值为 0.66。对于观察者内一致性,停顿的 Kappa 值为 0.47,中断的 Kappa 值为 0.65,尿流时间的 Kappa 值为 0.55,梗阻的 Kappa 值为 0.65。使用 3 分制(异常、中间、正常),观察者间一致性等于或高于 0.80。在第二次的 100 例尿流率中,观察者间一致性的 Kappa 值为停顿 0.44,中断 0.95,尿流时间 0.71,梗阻 0.73。
除了停顿外,尿流率曲线可以达到中等至较好的一致性。如果更精确地定义停顿和中断的流动,一致性会增加。停顿定义为超过最大流量平方根但不触及 0 的三个或更多峰谷,而中断流动至少需要一个 0 段。在正常、不间断的尿流中,尿流时间小于 15 秒。