化学-酶法合成多功能手性砌块分子，用于药物化合物的合成。
Chemo-enzymatic synthesis of a multi-useful chiral building block molecule for the synthesis of medicinal compounds.
机构信息
Department of Applied Molecular Bioscience, Graduate School of Medicine, Yamaguchi University, 2-16-1 Tokiwadai, Ube 755-8611, Japan.
出版信息
Molecules. 2011 Aug 9;16(8):6747-57. doi: 10.3390/molecules16086747.
Abstract
Optical resolution of 2-methyl-2-nitrobut-3-en-1-ol has been accomplished using a "low-temperature lipase-catalyzed transesterification" carried out at -40 °C.
摘要
采用“低温脂肪酶催化转酯化”在-40°C 下实现了 2-甲基-2-硝基-3-丁烯-1-醇的光学拆分。
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