前往热带非洲旅行者的疟疾预防

Malaria prophylaxis in travellers to tropical Africa.

作者信息

Weinke T, Weber G, Schultes U, Hopfenmüller W, Janitschke K

机构信息

II. Medizinische Klinik, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.

出版信息

Klin Wochenschr. 1990 Mar 5;68(5):277-80. doi: 10.1007/BF02116057.

DOI:10.1007/BF02116057

PMID:2182940

Abstract

This study investigated travellers to tropical Africa with regard to prophylactic treatment of malaria. A total of 5703 travellers completed a questionnaire on their flights back to the Federal Republic of Germany; 4116 passengers (73.7%) had visited East Africa, while 808 (14.5%) had been to West Africa. The results indicate that 90.2% took a regular chemoprophylaxis against malaria. Nevertheless, 8.1% of the travellers used no antimalarials and in 9.3% chemoprophylaxis was inadequate due to inappropriate advice; for example, 7.5% still took pyrimethamine-sulfadoxine as prophylactic. Mefloquine was correctly taken by 38.9% of the travellers in East Africa; 12.6% used it in West Africa where it is not necessary. Antimosquito measures have a high priority for travellers to tropical Africa and dissemination of this fact must be improved since only 72.6% followed through on such advice.

摘要

本研究对前往热带非洲的旅行者的疟疾预防性治疗情况进行了调查。共有5703名旅行者在返回德意志联邦共和国的航班上填写了问卷；4116名乘客（73.7%）去过东非，而808名（14.5%）去过西非。结果表明，90.2%的人进行了常规的疟疾化学预防。然而，8.1%的旅行者未使用抗疟药，9.3%的人因建议不当导致化学预防不足；例如，7.5%的人仍将乙胺嘧啶-磺胺多辛作为预防用药。在东非，38.9%的旅行者正确服用了甲氟喹；在西非，12.6%的人使用了甲氟喹，而在西非并无必要使用该药。对于前往热带非洲的旅行者而言，防蚊措施至关重要，必须加强这一信息的传播，因为只有72.6%的人遵循了此类建议。