• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

安大略省药品通用定价改革的短期影响。

The short-term impact of Ontario's generic pricing reforms.

机构信息

The Centre for Health Services and Policy Research, School of Population and Public Health, The University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

PLoS One. 2011;6(7):e23030. doi: 10.1371/journal.pone.0023030. Epub 2011 Jul 28.

DOI:10.1371/journal.pone.0023030
PMID:21829581
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3145787/
Abstract

BACKGROUND

Canadians pay amongst the highest generic drug prices in the world. In July 2010, the province of Ontario enacted a policy that halved reimbursement for generic drugs from the public drug plan, and substantially lowered prices for private purchases. We quantified the impact of this policy on overall generic drug expenditures in the province, and projected the impact in other provinces had they mimicked this pricing change.

METHODS

We used quarterly prescription generic drug dispensing data from the IMS-Brogan CompuScript Audit. We used the price per unit in both the pre- and post-policy period and two economics price indexes to estimate the expenditure reduction in Ontario. Further, we used the post-policy Ontario prices to estimate the potential reduction in other provinces.

RESULTS

We estimate that total expenditure on generic drugs in Ontario during the second half of 2010 was between $181 and $194 million below what would be expected if prices had remained at pre-policy level. Over half of the reduction in spending was due to savings on just 10 generic ingredients. If other provinces had matched Ontario's prices, their expenditures over during the latter half of 2010 would have been $445 million lower.

DISCUSSION

We found that if Ontario's pricing scheme were adopted nationally, overall spending on generic drugs in Canada would drop at least $1.28 billion annually--a 5% decrease in total prescription drug expenditure. Other provinces should seriously consider both changes to their generic drug prices and the use of more competitive bulk purchasing policies.

摘要

背景

加拿大的仿制药价格居全球最高之列。2010 年 7 月,安大略省出台了一项政策,将公共药品计划中仿制药的报销比例降低一半,并大幅降低私人购买仿制药的价格。我们量化了该政策对该省仿制药总支出的影响,并预测了其他省份效仿这一定价变化的影响。

方法

我们使用 IMS-Brogan CompuScript 审计的季度处方仿制药配药数据。我们使用政策前后的单位价格和两个经济价格指数来估计安大略省的支出减少情况。此外,我们使用安大略省的政策后价格来估计其他省份的潜在减少量。

结果

我们估计,2010 年下半年安大略省的仿制药总支出比如果价格保持在政策前水平,预计要低 1.81 亿至 1.94 亿美元。支出减少的一半以上是由于仅 10 种仿制药成分的节省。如果其他省份的价格与安大略省的价格相匹配,那么它们在 2010 年下半年的支出将减少 4.45 亿美元。

讨论

我们发现,如果安大略省的定价方案在全国范围内采用,加拿大的仿制药总支出每年至少将下降 12.8 亿美元——这将使处方药总支出减少 5%。其他省份应认真考虑调整仿制药价格和采用更具竞争力的大宗采购政策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06f5/3145787/41b176d3029e/pone.0023030.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06f5/3145787/41b176d3029e/pone.0023030.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06f5/3145787/41b176d3029e/pone.0023030.g001.jpg

相似文献

1
The short-term impact of Ontario's generic pricing reforms.安大略省药品通用定价改革的短期影响。
PLoS One. 2011;6(7):e23030. doi: 10.1371/journal.pone.0023030. Epub 2011 Jul 28.
2
Money left on the table: generic drug prices in Canada.被浪费的钱:加拿大的仿制药价格
Healthc Policy. 2013 Feb;8(3):17-25.
3
Impact of European pharmaceutical price regulation on generic price competition: a review.欧洲药品价格管制对仿制药价格竞争的影响:综述。
Pharmacoeconomics. 2010;28(8):649-63. doi: 10.2165/11535360-000000000-00000.
4
The impact of price-cap regulations on market entry by generic pharmaceutical firms.价格上限监管对仿制药公司市场进入的影响。
Expert Rev Pharmacoecon Outcomes Res. 2017 Apr;17(2):231-238. doi: 10.1080/14737167.2017.1271717. Epub 2016 Dec 27.
5
New generic pricing scheme maintains high prices and risks of shortages.新的仿制药定价方案维持了高价并带来了短缺风险。
CMAJ. 2018 Apr 9;190(14):E410-E411. doi: 10.1503/cmaj.180197.
6
European healthcare policies for controlling drug expenditure.欧洲控制药品支出的医疗政策。
Pharmacoeconomics. 2003;21(2):89-103. doi: 10.2165/00019053-200321020-00002.
7
The effect of generic competition on the price of brand-name drugs.仿制药竞争对品牌药价格的影响。
Health Policy. 2004 Apr;68(1):47-54. doi: 10.1016/j.healthpol.2003.07.007.
8
Ontario's plunging price-caps on generics: deeper dives may drown some drugs.安大略省大幅下调仿制药价格上限:深入探究可能会使一些药物陷入困境。
Open Med. 2011;5(3):e149-52. Epub 2011 Sep 27.
9
Generic drug prices and policy in Australia: room for improvement? a comparative analysis with England.澳大利亚的仿制药价格与政策:有改进空间吗?与英国的比较分析。
Aust Health Rev. 2014 Feb;38(1):6-15. doi: 10.1071/AH12009.
10
A Case Study of Pharmaceutical Pricing in China: Setting the Price for Off-Patent Originators.中国药品定价案例研究:为专利过期的原研药定价
Appl Health Econ Health Policy. 2015 Aug;13 Suppl 1(Suppl 1):S13-20. doi: 10.1007/s40258-014-0150-5.

引用本文的文献

1
Ontario and New Zealand Pharmaceuticals: Cost and Coverage.安大略省和新西兰的药品:成本与覆盖范围。
Healthc Policy. 2018 May;13(4):23-34. doi: 10.12927/hcpol.2018.25496.
2
Catastrophic drug coverage: utilization insights from the Ontario Trillium Drug Program.灾难性药物保险:安大略省延龄草药物计划的使用见解
CMAJ Open. 2018 Mar 14;6(1):E132-E138. doi: 10.9778/cmajo.20170132.
3
Trends in the use and cost of antipsychotics among older adults from 2007 to 2013: a repeated cross-sectional study.2007年至2013年老年人使用抗精神病药物的趋势及成本:一项重复横断面研究。

本文引用的文献

1
Geographic accessibility of community pharmacies in ontario.安大略省社区药房的地理可达性。
Healthc Policy. 2011 Feb;6(3):36-46. doi: 10.12927/hcpol.2011.22097.
2
Influencing Drug Prices through Formulary-Based Policies: Lessons from New Zealand.通过基于处方集的政策影响药品价格:来自新西兰的经验教训。
Healthc Policy. 2007 Aug;3(1):e121-40.
CMAJ Open. 2016 Jun 10;4(2):E292-7. doi: 10.9778/cmajo.20150095. eCollection 2016 Apr-Jun.
4
Pan-Canadian overpricing of medicines: a 6-country study of cost control for generic medicines.泛加拿大药品定价过高:一项关于仿制药成本控制的六国研究。
Open Med. 2014 Oct 14;8(4):e130-5. eCollection 2014.
5
Reformulation of controlled-release oxycodone and pharmacy dispensing patterns near the US-Canada border.美国-加拿大边境附近缓释羟考酮的重新配方及药房配药模式
Open Med. 2012 Nov 13;6(4):e141-5. Print 2012.