2005-2007 年巴西中西部孕妇丙型肝炎病毒感染情况。
Hepatitis C virus infection among pregnant women in Central-Western Brazil, 2005-2007.
机构信息
Programa Estadual de DST/Aids e Hepatites Virais, Secretaria de Estado de Saúde de Mato Grosso do Sul, Campo Grande, MS, Brasil.
出版信息
Rev Saude Publica. 2011 Oct;45(5):974-6. doi: 10.1590/s0034-89102011005000053. Epub 2011 Aug 5.
The study was aimed at estimating the prevalence of infection with and the genotype of hepatitis C virus (HCV), and to determine the extent of underreporting of HCV cases. A total of 115,386 pregnant women seen by the Program for Protection of Pregnancy [Programa Estadual de Proteção à Gestante] of the state of Mato Grosso do Sul, Central-Western Brazil, were tested for anti-HCV antibodies between 2005 and 2007. Prevalence of HCV infection was 1.07 cases per thousand. Positive samples were tested for HCV RNA and genotyped. Genotype 1 was detected in 73% of samples, genotype 3 in 24.3%, and genotype 2 in 2.7%. Underreporting of hepatitis C cases was 35.5%.
本研究旨在估算巴西中西部马托格罗索州妊娠保护项目（Programa Estadual de Proteção à Gestante）中 115386 名孕妇的丙型肝炎病毒（HCV）感染率和基因型，并确定 HCV 病例漏报的程度。2005 年至 2007 年间，对这些孕妇进行了抗-HCV 抗体检测。HCV 感染的流行率为每千例 1.07 例。对阳性样本进行 HCV RNA 检测和基因分型。73%的样本检测到基因型 1，24.3%的样本检测到基因型 3，2.7%的样本检测到基因型 2。丙型肝炎病例漏报率为 35.5%。
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