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老年急性髓细胞白血病的治疗(作者译)

[The treatment of acute myeloblastic leukemia in the elderly patients (author's transl)].

作者信息

Audebert A A, Hubert D, Krulik M, Debray J

出版信息

Sem Hop. 1979;55(1-2):90-2.

PMID:218302
Abstract

Thirty eight patients over 60 years with acute myeloblastic leukemia are studied. 16 p. cent (3 out 19) of the patients 60--69 year-old and 42 p. cent (8 out 19) over 70 died before any treatment or effective chemotherapy. Among the patients who received and effective chemotherapy, 48 p. cent responded and 7 complete remissions were obtained. The rate of responders is lower in oldest patients; nevertheless when a response whether complete or partial is observed, the survival of responders is dramatically improved. This invites to treat with effective chemotherapies every patients suffering from acute myeloblastic leukemia in the elderly. However, the comfort and the quality of survival must not be omitted.

摘要

对38例60岁以上的急性髓细胞白血病患者进行了研究。60至69岁的患者中有16%(19例中的3例)以及70岁以上的患者中有42%(19例中的8例)在接受任何治疗或有效化疗之前死亡。在接受有效化疗的患者中,48%有反应,获得了7例完全缓解。年龄最大的患者中反应者的比例较低;然而,当观察到有完全或部分反应时,反应者的生存率会显著提高。这促使对每一位老年急性髓细胞白血病患者都采用有效化疗进行治疗。然而,舒适度和生存质量也不容忽视。

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