Treckmann Jürgen W, Goldenberg Andrej, Malamutmann Eugen, Witzke Oliver, Fouzas Ioannis, Paul Andreas, Sotiropoulos Georgios C
Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany.
Hepatogastroenterology. 2011 May-Jun;58(107-108):738-9.
BACKGROUND/AIMS: The aim of this study was to analyze the risk for surgical complications after kidney transplantation in patients with diabetes mellitus (DM) compared to patients without DM.
Between January 2002 and December 2005 270 consecutive kidney transplantations from deceased donors in adult recipients were performed. Data of these patients were analyzed on the presence of DM. Recipients with DM (n=32) were compared with patients without DM (n=238) concerning delayed graft function, wound infections, urinary leakage, postoperative bleeding and urinary infections.
No statistically significant differences were found in the occurrence of delayed graft function, postoperative bleeding and urinary tract infections between both groups. Although the percentage of postoperative wound infections and urinary leakages was elevated in the DM group it was not statistical significant.
In patients with terminal kidney insufficiency the presence of DM type II is a frequent co-morbidity and is per se not a contraindication for kidney transplantation. Because of the elevated cardiovascular risk profile patients with DM have to be evaluated very diligent before being listed for kidney transplantation. Nevertheless beside the additional short term risk caused by kidney transplantation it is the only modifiable risk with possible long term reduction for these patients.
背景/目的：本研究旨在分析糖尿病（DM）患者与非糖尿病患者肾移植术后手术并发症的风险。
2002年1月至2005年12月，对成年受者中270例连续进行的尸体供肾移植进行研究。分析这些患者的糖尿病情况。将糖尿病患者（n = 32）与非糖尿病患者（n = 238）在移植肾功能延迟、伤口感染、尿漏、术后出血和泌尿系统感染方面进行比较。
两组在移植肾功能延迟、术后出血和泌尿系统感染的发生率上未发现统计学显著差异。虽然糖尿病组术后伤口感染和尿漏的百分比有所升高，但无统计学意义。
在终末期肾功能不全患者中，II型糖尿病是常见的合并症，本身并非肾移植的禁忌症。由于糖尿病患者心血管风险增加，在列入肾移植名单前必须对其进行非常仔细的评估。然而，除了肾移植带来的额外短期风险外，这是这些患者唯一可改变且可能长期降低的风险。
