Kim Byung Seup, Cho Sung Wook, Min Soo Kee, Lee Bong Hwa
Department of Surgery, Hallym University College of Medicine, Anyang, Korea.
Hepatogastroenterology. 2011 May-Jun;58(107-108):1032-40.
BACKGROUND/AIMS: The aim of this study was to assess any differences in the prognostic factors affecting long term survival in early gastric cancer (EGC) and advanced gastric cancer (AGC).
The prognostic factors affecting long term survival between EGC and AGC were evaluated.
Based on the result of multivariate analysis, the variables related with poor prognosis in patient with EGC were ages of more than 60 (p=0.003, Relative risk [RR]:2.683) and more than 7 lymph nodes with metastasis (p=0.001, RR:12.129). The relevant variables in AGC were the presence of more than 7 lymph nodes with metastasis (p=0.002, RR:2.491), lymphovascular invasion (p=0.038, RR:1.476) and tumor depth (serosa ; p<0.001, RR:3.493, adjacent structure; p=0.005, RR:3.013).
The prognostic factors affecting long term survival are a little different between the patients with EGC and AGC. Age of more than 60 years is one of the prognostic factors affecting long term survival in patients with EGC, but not with AGC. In AGC, lymphovascular invasion and tumor depth are prognostic factors but not in EGC.
背景/目的：本研究旨在评估影响早期胃癌（EGC）和进展期胃癌（AGC）长期生存的预后因素的差异。
评估影响EGC和AGC长期生存的预后因素。
基于多因素分析结果，EGC患者预后不良相关的变量为年龄大于60岁（p = 0.003，相对风险[RR]：2.683）和有7个以上淋巴结转移（p = 0.001，RR：12.129）。AGC的相关变量为有7个以上淋巴结转移（p = 0.002，RR：2.491）、淋巴管侵犯（p = 0.038，RR：1.476）和肿瘤深度（浆膜层；p < 0.001，RR：3.493，邻近结构；p = 0.005，RR：3.013）。
影响EGC和AGC患者长期生存的预后因素略有不同。年龄大于60岁是影响EGC患者长期生存的预后因素之一，但不是AGC的预后因素。在AGC中，淋巴管侵犯和肿瘤深度是预后因素，但在EGC中不是。
