Deckard Nathan A, Kruper Gregory J, Bui Thi, Coticchia James
Wayne State University, Department of Otolaryngology, Head and Neck Surgery, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Int J Pediatr Otorhinolaryngol. 2011 Oct;75(10):1296-300. doi: 10.1016/j.ijporl.2011.07.015. Epub 2011 Aug 10.
To compare two minimally invasive techniques for the treatment of chronic rhinosinusitis in young children.
Chronic rhinosinusitis (CRS) is a common diagnosis in young children. Maxillary sinus aspiration & irrigation with adenoidectomy (MSI) followed by an extended course of oral antibiotics has been shown to be an alternative to functional endoscopic sinus surgery. However, since MSI is not performed under direct visualization, it has inherent risk. This study analyzes the techniques of MSI and endoscopically guided middle meatus cultures & antral biopsy with adenoidectomy (EGC) in the (1) diagnosis of bacterial infection by culture, (2) time to resolution using double antibiotic therapy, and (3) associated morbidity of the two procedures.
The medical records at Wayne State University, Department of Otolaryngology Head & Neck Surgery were reviewed from 2004 to 2010. All children who presented with CRS who underwent MSI or EGC were included in this retrospective case series.
Patients presented with a history of cough, nasal discharge, and congestion. The mean age was 3.7 years. Symptom duration prior to treatment was 7.4 months in the 64 patients who underwent MSI and 9.1 months in the 46 patients who underwent EGC. MSI identified bacteria in 80% of patients compared to 73% in EGC patients (p=0.45). The MSI group underwent antibiotic treatment for 8.7 weeks and achieved symptom resolution in 8.7 weeks compared to 6.9 weeks and 4.9 weeks respectively in the EGC group (p=0.08 and 0.01). However, if patients presented with snoring or cough, time to resolution of symptoms was significantly lower in patients undergoing EGC versus MSI (p=0.02 and p=0.01, respectively). One patient who underwent MSI experienced epistaxis requiring nasal packing, and two patients had pseudoproptosis following irrigation that resolved spontaneously shortly thereafter. No complications were reported in the EGC group.
EGC is an effective treatment for young children with CRS. EGC and MSI are equally effective in obtaining diagnostic cultures. EGC decreases time to symptom resolution, and it lowers the risk of complication when compared to MSI.
比较两种治疗幼儿慢性鼻-鼻窦炎的微创技术。
慢性鼻-鼻窦炎(CRS)在幼儿中是一种常见诊断。上颌窦穿刺冲洗联合腺样体切除术(MSI),随后延长口服抗生素疗程,已被证明是功能性内镜鼻窦手术的一种替代方法。然而,由于MSI不是在直视下进行,存在固有风险。本研究分析了MSI技术以及内镜引导下中鼻道培养及窦腔活检联合腺样体切除术(EGC)在以下方面的情况:(1)通过培养诊断细菌感染;(2)使用双重抗生素治疗至症状缓解的时间;(3)两种手术相关的发病率。
回顾了韦恩州立大学耳鼻喉头颈外科2004年至2010年的病历。所有患有CRS且接受MSI或EGC的儿童均纳入本回顾性病例系列。
患者表现出咳嗽、流涕和鼻塞病史。平均年龄为3.7岁。接受MSI的64例患者治疗前症状持续时间为7.4个月,接受EGC的46例患者为9.1个月。MSI在80%的患者中鉴定出细菌,而EGC患者中这一比例为73%(p = 0.45)。MSI组接受抗生素治疗8.7周,症状在8.7周时缓解,而EGC组分别为6.9周和4.9周(p = 0.08和0.01)。然而,如果患者出现打鼾或咳嗽,接受EGC的患者症状缓解时间明显短于接受MSI的患者(分别为p = 0.02和p = 0.01)。1例接受MSI的患者发生鼻出血需要鼻腔填塞,2例患者冲洗后出现假性眼球突出,此后不久自行缓解。EGC组未报告并发症。
EGC是治疗幼儿CRS的有效方法。EGC和MSI在获取诊断性培养物方面同样有效。与MSI相比,EGC缩短了症状缓解时间,并降低了并发症风险。