Dubey Mohan Lal, Khurana Sumeeta, Singhal Lipika, Dogra Shivani, Singh Surjit
Department of Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Trop Doct. 2011 Oct;41(4):244-6. doi: 10.1258/td.2011.110106. Epub 2011 Aug 10.
Human trichinellosis is an important food-borne zoonosis caused by a nematode worm, Trichinella. The symptoms of the disease vary widely depending on the infection load, stage of infection and host immunity and include nausea, vomiting, abdominal pain, fever, facial edema and muscle pain. The disease is usually characterized by moderate to high eosinophilia. We hereby discuss an atypical case of trichinellosis, which presented with myositis of the thigh muscles but had no eosinophilia and no facial or periorbital edema and was associated with osteomyelitis of the femur. The diagnosis was made by the demonstration of anti-trichinella antibodies and later confirmed by the presence of larvae of Trichinella in the digested muscle biopsy. Physicians must be aware of trichinosis and should include it in their differential diagnosis when examining patients with fever and myositis with or without eosinophilia.
人体旋毛虫病是一种由线虫旋毛虫引起的重要食源性人畜共患病。该病症状因感染负荷、感染阶段和宿主免疫力的不同而有很大差异，包括恶心、呕吐、腹痛、发热、面部水肿和肌肉疼痛。该病通常以中度至高度嗜酸性粒细胞增多为特征。我们在此讨论一例非典型旋毛虫病病例，该病例表现为大腿肌肉肌炎，但无嗜酸性粒细胞增多，无面部或眶周水肿，且与股骨骨髓炎有关。通过检测抗旋毛虫抗体做出诊断，随后在消化的肌肉活检中发现旋毛虫幼虫得以确诊。医生必须了解旋毛虫病，在检查有发热和肌炎（无论有无嗜酸性粒细胞增多）的患者时，应将其纳入鉴别诊断。
