Kanzaki Sho, Saito Hideyuki, Mori Tetsuya, Shimasaki Noriko, Mukai Makio, Ogawa Kaoru
Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, Tokyo, Japan.
ORL J Otorhinolaryngol Relat Spec. 2011;73(5):266-70. doi: 10.1159/000330386. Epub 2011 Aug 11.
Non-Hodgkin diffuse large B-cell lymphomas of the mastoid that extend from the nasopharynx are extremely rare in children. Moreover, in lymphoproliferative diseases, the presence of otoneurological signs prior to systemic disease involvement is rare. Here, we present a rare case of non-Hodgkin B-cell lymphoma invading the middle ear and mastoid in a 1-year-old boy that mimicked acute mastoiditis with complete facial nerve palsy. As this case illustrates, physicians should consider a diagnosis of malignant lymphoma if a patient presents with otitis media and mastoiditis accompanied by facial palsy.
起源于鼻咽部并累及乳突的非霍奇金弥漫性大B细胞淋巴瘤在儿童中极为罕见。此外,在淋巴增殖性疾病中,在全身性疾病累及之前出现耳神经学症状的情况也很少见。在此,我们报告一例罕见病例,一名1岁男孩患有非霍奇金B细胞淋巴瘤侵犯中耳和乳突,表现类似急性乳突炎并伴有完全性面神经麻痹。正如本病例所示,如果患者出现中耳炎和乳突炎并伴有面神经麻痹,医生应考虑恶性淋巴瘤的诊断。