Neve J
Université Libre de Bruxelles, Laboratoire de Chimie Pharmaceutique Organique, Belgique.
Rev Fr Gynecol Obstet. 1990 Jan;85(1):29-33.
Selenium is an essential trace element with protective properties against endogenous or exogenous aggression, mainly due to the hyperproduction of oxygen derivatives. During pregnancy, a depletion in plasma selenium occurs regulated by hormones from the placenta. Selenium requirement is simultaneously increased which is partly satisfied by the increased retention of the element resulting from a decrease in selenium urinary excretion. The foetus accumulates selenium at the end of pregnancy by storing it in the liver. However, after birth, selenium stores rapidly deplete. Selenium deficiency is apparently not responsible for pregnancy or delivery problems in man. However, the infant is exposed to pronounced deficiency symptoms or to the worsening of some diseases liable to affect the young baby, particularly if premature because the usual selenium dietary intake is marginal in this country, selenium supplementation with 25 to 50 micrograms selenium per day is advisable and should be considered among other trace elements as a food supplement for pregnant and lactating woman.
硒是一种必需的微量元素，具有抵御内源性或外源性侵害的保护特性，主要是由于氧衍生物的过度产生。在怀孕期间，血浆硒的含量会因胎盘激素的调节而减少。同时，硒的需求量会增加，这部分通过尿硒排泄减少导致的元素潴留增加而得到满足。胎儿在妊娠末期通过将硒储存在肝脏中来积累硒。然而，出生后，硒储备会迅速耗尽。硒缺乏显然不是导致人类妊娠或分娩问题的原因。然而，婴儿会出现明显的缺乏症状，或某些易影响幼儿的疾病会恶化，特别是如果早产，因为在这个国家，通常的硒膳食摄入量处于边缘水平，建议每天补充25至50微克硒，并且应将其与其他微量元素一起视为孕妇和哺乳期妇女的食物补充剂。
