Department of Dermatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Australas J Dermatol. 2011 Aug;52(3):231-2. doi: 10.1111/j.1440-0960.2011.00729.x. Epub 2011 Mar 1.
We report the patchy normalization of lamellar ichthyotic skin in Sjögren-Larsson syndrome (SLS) following a cutaneous Trichophyton rubrum infection. The dermatophytosis was pruritic and pustular, requiring treatment which was followed by the return of the lamellar ichthyosis. We discuss the possible mechanism of this clinical observation, which in turn may direct future therapy for difficult to treat ichthyotic skin seen in conditions such as SLS.
我们报告一例 Sjögren-Larsson 综合征（SLS）患者在感染皮肤癣菌（Trichophyton rubrum）后出现板层状鱼鳞癣皮肤的斑片状正常化。这种皮肤癣菌病伴有瘙痒和脓疱，需要治疗，随后板层状鱼鳞癣又复发了。我们讨论了这种临床观察的可能机制，这反过来可能为 SLS 等疾病中治疗棘手的鱼鳞癣皮肤提供新的治疗方向。
