Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan.
Int J Urol. 2011 Oct;18(10):686-90. doi: 10.1111/j.1442-2042.2011.02830.x. Epub 2011 Aug 11.
Contrast-induced nephropathy (CIN) is a serious complication resulting from the use of iodinated contrast medium (CM) with potentially high morbidity and mortality. Patients with pre-existing renal insufficiency appear to be at higher risk of CIN. To prevent CIN among patients undergoing contrast-enhanced computed tomography, every effort is required, including routine identification of at-risk patients, the use of appropriate hydration regimens, withdrawal of nephrotoxic drugs, selection of low-osmolality CM or iso-osmolar CM, and using the minimum volume of CM possible.
对比剂肾病（CIN）是使用碘造影剂（CM）后可能导致的严重并发症，具有较高的发病率和死亡率。有基础肾功能不全的患者似乎面临更高的 CIN 风险。为预防行增强 CT 检查的患者发生 CIN，需要采取一切措施，包括常规识别高危患者、使用合适的水化方案、停用肾毒性药物、选择低渗或等渗 CM 以及尽可能减少 CM 用量。
