Plotton I, Brosse A, Lejeune H
Service de médecine de la reproduction, hôpital Femme-Mère-Enfant, CHU de Lyon, 59 boulevard Pinel, Bron, France.
Gynecol Obstet Fertil. 2011 Sep;39(9):529-32. doi: 10.1016/j.gyobfe.2011.07.002. Epub 2011 Aug 10.
Until few years ago, Klinefelter syndrome with a homogenous 47.XXY caryotype was considered a model of absolute male sterility. In this review, we will discuss the fertility issue following TEsticular Sperm Extraction-IntraCytoplasmic Sperm Injection (TESE-ICSI) and the potential advantage of searching for and cryopreserving spermatozoa in adolescent instead of adult patients.