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[Infertility treatment in Klinefelter syndrome].

作者信息

Plotton I, Brosse A, Lejeune H

机构信息

Service de médecine de la reproduction, hôpital Femme-Mère-Enfant, CHU de Lyon, 59 boulevard Pinel, Bron, France.

出版信息

Gynecol Obstet Fertil. 2011 Sep;39(9):529-32. doi: 10.1016/j.gyobfe.2011.07.002. Epub 2011 Aug 10.

DOI:10.1016/j.gyobfe.2011.07.002
PMID:21835671
Abstract

Until few years ago, Klinefelter syndrome with a homogenous 47.XXY caryotype was considered a model of absolute male sterility. In this review, we will discuss the fertility issue following TEsticular Sperm Extraction-IntraCytoplasmic Sperm Injection (TESE-ICSI) and the potential advantage of searching for and cryopreserving spermatozoa in adolescent instead of adult patients.

摘要

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[Infertility treatment in Klinefelter syndrome].
Gynecol Obstet Fertil. 2011 Sep;39(9):529-32. doi: 10.1016/j.gyobfe.2011.07.002. Epub 2011 Aug 10.
2
Klinefelter syndrome and TESE-ICSI.克兰费尔特综合征与睾丸切开取精术-卵胞浆内单精子注射
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Preliminary results of a prospective study of testicular sperm extraction in young versus adult patients with nonmosaic 47,XXY Klinefelter syndrome.针对非嵌合型47,XXY克氏综合征年轻患者与成年患者进行睾丸精子提取的前瞻性研究的初步结果。
J Clin Endocrinol Metab. 2015 Mar;100(3):961-7. doi: 10.1210/jc.2014-3083. Epub 2014 Nov 25.
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[Intracytoplasmic sperm injection for Klinefelter patients and the risk of chromosome anomaly in the patients' offspring].[克氏综合征患者的卵胞浆内单精子注射及患者后代染色体异常风险]
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The feasibility of fertility preservation in adolescents with Klinefelter syndrome.青春期克莱恩费尔特综合征患者生育力保存的可行性。
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Testicular biopsy and cryopreservation for fertility preservation of prepubertal boys with Klinefelter syndrome: a pro/con debate.睾丸活检及冷冻保存用于克氏综合征青春期前男孩生育力保存:正反方辩论
Fertil Steril. 2016 Feb;105(2):249-55. doi: 10.1016/j.fertnstert.2015.12.011. Epub 2015 Dec 31.
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[Fertility in Klinefelter syndrome].[克兰费尔特综合征的生育能力]
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Birth of healthy male twins after intracytoplasmic sperm injection of frozen-thawed testicular spermatozoa from a patient with nonmosaic Klinefelter syndrome.对一名非嵌合型克兰费尔特综合征患者冻融后的睾丸精子进行卵胞浆内单精子注射后,诞生了健康的男性双胞胎。
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引用本文的文献

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Testicular Tissue Banking for Fertility Preservation in Young Boys: Which Patients Should Be Included?睾丸组织库用于保存年轻男孩的生育能力:哪些患者应包括在内?
Front Endocrinol (Lausanne). 2022 Mar 10;13:854186. doi: 10.3389/fendo.2022.854186. eCollection 2022.
2
Is there any clinical relevant difference between non mosaic Klinefelter Syndrome patients with or without Androgen Receptor variations?非嵌合体 Klinefelter 综合征患者是否存在雄激素受体变异与无雄激素受体变异之间的临床相关差异?
Sci Rep. 2017 Jun 13;7(1):3358. doi: 10.1038/s41598-017-03371-y.
3
Twin Pregnancy Obtention of Patient with Nonmosaic Klinefelter's Syndrome and His Wife with Chromosome 9 Inversion by ICSI Treatment.
非嵌合型克兰费尔特综合征患者及其染色体9倒位妻子通过卵胞浆内单精子注射治疗获得双胎妊娠
Int J Fertil Steril. 2013 Jul;7(2):142-6. Epub 2013 Jul 31.