早期肠内营养对降低胃癌根治术并发症有帮助吗？

[Does contribute early enteral nutrition to decrease the complications of radical gastrectomy for gastric cancer?].

作者信息

Delgado Delgado Ronald Christian, Luque Vásquez Carlos E

机构信息

Médico Asistente del Servicio de Cirugía General del Hospital IV Alberto Sabogal Sologuren.

出版信息

Rev Gastroenterol Peru. 2011 Apr-Jun;31(2):146-50.

PMID:21836655

Abstract

OBJECTIVE

To evaluate whether the administration of early enteral nutrition in postoperative gastrectomized patients due gastric cancer helps to reduce the frequency of postoperative complications.

MATERIALS AND METHODS

A case-control study with 120 patients, 60 with postoperative complications (cases) and 60 patients without post operative complications (controls) matched for age and sex.

RESULTS

The uni-variable analysis found that albumin (p=0.03), hematocrit (p=0.004), early enteral nutrition (p<0.01), stage of gastric cancer (p=0.013), behaved as variables associated with the development of postoperative complications. However, in this multivariable analysis, only early enteral nutrition (p=0.014), hematocrit (0.019) and pathological stage (0.013), showed statistically significant association.

CONCLUSIONS

The early enteral nutrition administered by nasoenteral tube in the immediate postoperative period, with the hematocrit level and the anatomopathological disease stage is associated with statistically decreased postoperative complications in patients undergoing radical surgery for gastric cancer.

摘要

目的

评估胃癌胃切除术后早期肠内营养的给予是否有助于降低术后并发症的发生率。

材料与方法

一项病例对照研究，纳入120例患者，其中60例有术后并发症（病例组），60例无术后并发症（对照组），两组在年龄和性别上相匹配。

结果

单变量分析发现，白蛋白（p = 0.03）、血细胞比容（p = 0.004）、早期肠内营养（p < 0.01）、胃癌分期（p = 0.013）与术后并发症的发生相关。然而，在多变量分析中，只有早期肠内营养（p = 0.014）、血细胞比容（0.019）和病理分期（0.013）显示出统计学上的显著关联。