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5-氯-3-环戊基亚磺酰基-2-甲基-1-苯并呋喃

5-Chloro-3-cyclo-pentyl-sulfinyl-2-methyl-1-benzofuran.

作者信息

Seo Pil Ja, Choi Hong Dae, Son Byeng Wha, Lee Uk

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1557. doi: 10.1107/S1600536811019775. Epub 2011 Jun 4.

DOI:10.1107/S1600536811019775
PMID:21836971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3151758/
Abstract

In the title compound, C(14)H(15)ClO(2)S, the cyclo-pentyl ring adopts an envelope conformation. In the crystal, mol-ecules are linked through weak inter-molecular C-H⋯O hydrogen bonds. The crystal structure also exhibits a slipped π-π inter-action between the furan and benzene rings of neighbouring mol-ecules [centroid-centroid distance = 3.784 (3) Å, inter-planar distance = 3.199 (3) Å and slippage = 2.021 (3) Å].

摘要

在标题化合物C₁₄H₁₅ClO₂S中,环戊基环呈信封式构象。在晶体中,分子通过弱的分子间C—H⋯O氢键相连。晶体结构还显示出相邻分子的呋喃环和苯环之间存在滑移π-π相互作用[质心间距 = 3.784(3) Å,平面间距 = 3.199(3) Å,滑移 = 2.021(3) Å]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a85/3151758/5c520d8b835b/e-67-o1557-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a85/3151758/23da758319b3/e-67-o1557-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a85/3151758/5c520d8b835b/e-67-o1557-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a85/3151758/23da758319b3/e-67-o1557-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a85/3151758/5c520d8b835b/e-67-o1557-fig2.jpg

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本文引用的文献

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Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1386. doi: 10.1107/S1600536811017120. Epub 2011 May 11.
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Synthesis of potent antitumor and antiviral benzofuran derivatives.强效抗肿瘤和抗病毒苯并呋喃衍生物的合成。
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A short history of SHELX.SHELX简史。
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Antibacterial and antifungal activity of cicerfuran and related 2-arylbenzofurans and stilbenes.鹰嘴豆呋喃及相关2-芳基苯并呋喃和芪类化合物的抗菌和抗真菌活性。
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A new structural alternative in benzo[b]furans for antimicrobial activity.苯并[b]呋喃类化合物中一种具有抗菌活性的新结构变体。
Bioorg Med Chem. 2005 Aug 15;13(16):4796-805. doi: 10.1016/j.bmc.2005.05.009.
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Artoindonesianins X and Y, two isoprenylated 2-arylbenzofurans, from Artocarpus fretessi (Moraceae).从桑科植物菲律宾波罗蜜(Artocarpus fretessi)中提取的两种异戊二烯化的2-芳基苯并呋喃类化合物,即印度尼西亚波罗蜜素X和Y。
Phytochemistry. 2003 Oct;64(4):831-4. doi: 10.1016/j.phytochem.2003.08.009.
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Benzofurans and another constituent from seeds of Styrax officinalis.苯并呋喃及来自药用安息香种子的另一种成分。
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