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高剂量西酞普兰治疗退伍军人可卡因依赖的初步研究

High-dose citalopram for cocaine dependence in veteran population-a pilot project.

出版信息

Am J Addict. 2011 Sep-Oct;20(5):485-6. doi: 10.1111/j.1521-0391.2011.00162.x. Epub 2011 Jul 18.

DOI:10.1111/j.1521-0391.2011.00162.x
PMID:21838852
Abstract

Cocaine dependence continues to be a highly prevalent disorder, which is associated with significant morbidity and mortality. Numerous medications have been investigated as potential adjunctive therapeutic measures, but with minimal success. None have been given Food and Drug Administration approval for treatment of cocaine dependence. (Am J Addict 2011;00:1-2).

摘要

可卡因依赖仍是一种高发疾病,与严重发病率和死亡率相关。许多药物已被研究作为潜在的辅助治疗措施,但收效甚微。尚无药物获得美国食品和药物管理局批准用于治疗可卡因依赖。(《美国药物依赖杂志》2011 年;00:1-2)。

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High-dose citalopram for cocaine dependence in veteran population-a pilot project.高剂量西酞普兰治疗退伍军人可卡因依赖的初步研究
Am J Addict. 2011 Sep-Oct;20(5):485-6. doi: 10.1111/j.1521-0391.2011.00162.x. Epub 2011 Jul 18.
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Olanzapine for cocaine craving and relapse prevention in 2 patients.奥氮平用于2例可卡因渴求及预防复吸的治疗
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Clinical efficacy of citalopram alone or augmented with bupropion in methadone-stabilized patients.西酞普兰单药治疗或联合安非他酮对美沙酮维持治疗患者的临床疗效。
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引用本文的文献

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Addictive behaviour in experimental animals: prospects for translation.实验动物的成瘾行为:转化的前景。
Philos Trans R Soc Lond B Biol Sci. 2018 Mar 19;373(1742). doi: 10.1098/rstb.2017.0027.
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Moderators of response to sertraline versus placebo among recently abstinent, cocaine dependent patients: A retrospective analysis of two clinical trials.
近期戒断的可卡因依赖患者中舍曲林与安慰剂反应的调节剂:两项临床试验的回顾性分析。
Am J Addict. 2017 Dec;26(8):807-814. doi: 10.1111/ajad.12635. Epub 2017 Nov 8.
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Neural and psychological mechanisms underlying compulsive drug seeking habits and drug memories--indications for novel treatments of addiction.强迫性觅药习惯和药物记忆背后的神经及心理机制——成瘾新疗法的指征
Eur J Neurosci. 2014 Jul;40(1):2163-82. doi: 10.1111/ejn.12644. Epub 2014 Jun 17.
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J Clin Psychopharmacol. 2014 Apr;34(2):234-9. doi: 10.1097/JCP.0000000000000062.
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Reduced forebrain serotonin transmission is causally involved in the development of compulsive cocaine seeking in rats.大脑前部血清素传递减少与大鼠强迫性可卡因觅药行为的发展有因果关系。
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