Department of Surgery, Colorectal Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Clin Colorectal Cancer. 2011 Dec;10(4):291-7. doi: 10.1016/j.clcc.2011.06.001. Epub 2011 Aug 15.
This review contains a surgical perspective on the evolution of the nonoperative approach to patients with locally advanced rectal cancer who have a clinical complete response after neoadjuvant combined modality therapy, including accuracy of pathologic complete response identification, the timing between neoadjuvant combined modality therapy and assessment of response, the extent of long-term follow-up, and the likelihood of surgical salvage after an initial nonoperative approach.
这篇综述从手术角度探讨了新辅助联合治疗后临床完全缓解的局部进展期直肠癌患者的非手术治疗方法的演变，包括病理完全缓解识别的准确性、新辅助联合治疗与评估反应之间的时间间隔、长期随访的程度以及初始非手术治疗后手术挽救的可能性。
