Piper H F
Gesnerus. 1990;47 Pt 1:83-94.
Between 1888 and 1892, Mikulicz as well as Fuchs observed each a case of oculo-salivary glandular syndrome. Ten years later, Heerfordt described uveitis complicated by swelling of the lacrimal and salivary glands. Within 100 years, the interpretation of this disease changed repeatedly and considerably: infection of particularly exposed organs--non-avirulent tuberculosis--salivotropic virus--Boeck's disease--allergic-hyperergic reaction--diencephalic and nervous dystrophy with segmental projection--(auto)immune disease--oculo-salivary complex including Sjøgren's syndrome--all these were discussed as possible aetiologies. Short biographies of Johannes von Mikulicz-Radecki, surgeon at Austrian and Prussian universities; Ernst Fuchs, ophthalmologist of Vienna; Christian Frederik Heerfordt, a Danish ophthalmologist particularly fond of publicity.
1888年至1892年间，米库利奇（Mikulicz）和富克斯（Fuchs）各自观察到一例眼-唾液腺综合征病例。十年后，黑尔福特（Heerfordt）描述了伴有泪腺和唾液腺肿大的葡萄膜炎。在100年的时间里，对这种疾病的解释反复且大幅地发生了变化：特别暴露器官的感染——非致病性结核——嗜唾液病毒——伯克氏病——过敏-超敏反应——伴有节段性投射的间脑和神经营养不良——（自身）免疫性疾病——包括干燥综合征在内的眼-唾液复合体——所有这些都被作为可能的病因进行了讨论。约翰内斯·冯·米库利奇-拉德茨基（Johannes von Mikulicz-Radecki）的简短生平，奥地利和普鲁士大学的外科医生；维也纳眼科医生恩斯特·富克斯（Ernst Fuchs）；特别喜欢出风头的丹麦眼科医生克里斯蒂安·弗雷德里克·黑尔福特（Christian Frederik Heerfordt）。
