Infante-Cossio Pedro, Gonzalez-Cardero Eduardo, Gonzalez-Perez Luis-Miguel, Leopoldo-Rodado Manuel, Garcia-Perla Alberto, Esteban Francisco
Department of Oral and Maxillofacial Surgery, Virgen del Rocio University Hospital, Manuel Siurot Av, 41013, Seville, Spain.
Oral Maxillofac Surg. 2011 Dec;15(4):211-6. doi: 10.1007/s10006-011-0289-2. Epub 2011 Aug 13.
Pleomorphic adenoma (PA) is found rarely in the parapharyngeal space (PPS). Because of late diagnosis due to slow growth, close proximity to vital neurovascular structures and risks of surgery, it poses a great difficulty for both diagnosis and surgical management. The preferred surgical approach to the PPS is the cervical-transparotid including a total parotidectomy with facial nerve preservation combined with a cervical access for dissection of cranial nerves and vascular structures thus allowing a safe removal of the tumor together with the parotid deep lobe. We report herein our experience in the management of giant PAs involving the prestyloid PPS and describe a not well-documented transparotid route by preservation of the parotid superficial lobe in combination with an intraoral approach.
In this retrospective study, three cases of patients having giant PAs involving the PPS are evaluated. All patients had signs of foreign body sensation in the throat and a growing mass bulging in the oropharynx. Diagnosis was based on MRI and upon preoperative intraoral biopsy. The average tumor size was 5.7 cm. Patients underwent surgery and excision of tumors via transparotid-intraoral approach. In two cases, the superficial lobe was preserved and afterwards put back in its anatomic location.
All patients were discharged without complications, and no recurrences were observed.
Preoperative diagnosis management of PPS giant tumors should be based on imaging and upon open transoral biopsy if possible. The transparotid-intraoral approach provided adequate visibility to remove large PAs involving the prestyloid PPS.
多形性腺瘤(PA)在咽旁间隙(PPS)中很少见。由于其生长缓慢导致诊断延迟,且紧邻重要的神经血管结构以及存在手术风险,这给诊断和手术治疗都带来了极大困难。PPS首选的手术入路是颈腮腺入路,包括保留面神经的全腮腺切除术以及通过颈部入路解剖颅神经和血管结构,从而能够安全地切除肿瘤及腮腺深叶。我们在此报告我们处理累及茎突前PPS的巨大PA的经验,并描述一种通过保留腮腺浅叶并结合口内入路的、文献记载较少的腮腺入路。
在这项回顾性研究中,评估了3例患有累及PPS的巨大PA的患者。所有患者均有咽部异物感以及口咽内肿物逐渐增大的症状。诊断基于MRI及术前口内活检。肿瘤平均大小为5.7厘米。患者通过腮腺口内入路接受手术并切除肿瘤。2例患者保留了浅叶,随后将其放回解剖位置。
所有患者均无并发症出院,且未观察到复发情况。
PPS巨大肿瘤的术前诊断处理应基于影像学检查,如有可能应进行开放经口活检。腮腺口内入路为切除累及茎突前PPS的大型PA提供了足够的视野。